CAS 15761-39-4
:BOC-L-Proline
Description:
BOC-L-Proline, with the CAS number 15761-39-4, is a derivative of the amino acid proline, characterized by the presence of a tert-butyloxycarbonyl (BOC) protecting group. This compound is commonly used in peptide synthesis as a protecting group for the amino group of proline, facilitating the formation of peptide bonds without unwanted side reactions. BOC-L-Proline is typically a white to off-white crystalline solid, and it is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. The BOC group is easily removed under acidic conditions, allowing for the regeneration of the free amino group for further reactions. This compound plays a significant role in the synthesis of various peptides and pharmaceuticals, making it valuable in medicinal chemistry and biochemistry. Its stability, ease of handling, and compatibility with various reaction conditions contribute to its widespread use in synthetic organic chemistry.
Formula:C10H17NO4
InChI:InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/p-1/t7-/m0/s1
InChI key:InChIKey=ZQEBQGAAWMOMAI-ZETCQYMHSA-N
SMILES:C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)CCC1
Synonyms:- (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
- (2S)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
- (2S)-1-Boc-pyrrolidine-2-carboxylic acid
- (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
- (2S)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid
- (S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
- (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinecarboxylic acid
- (S)-1-Boc-β-proline
- (S)-N-tert-Butoxycarbonylproline
- (S)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
- 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-
- 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (S)-
- 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-
- 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, L-
- 1-(Tert-Butoxycarbonyl)Proline
- 1-(tert-Butoxycarbonyl)-(2S)-pyrrolidine-2-carboxylic acid
- 1-(tert-Butoxycarbonyl)-(S)-proline
- 1-(tert-Butyl)hydrogen-(S)-pyrrolidin-1,2-dicarboxylat
- 1-(tert-butoxycarbonyl)-L-proline
- 1-(tert-butyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
- 1-Boc-L-Proline
- 1-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-proline
- 1-tert-Butyl (S)-pyrrolidine-1,2-dicarboxylate
- 1-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
- 1-tert-Butyloxycarbonyl-L-proline
- <span class="text-smallcaps">L</span>-N-Boc-proline
- BOC-<span class="text-smallcaps">L</span>-Proline
- Boc-<span class="text-smallcaps">L</span>-Pro
- Boc-L-Pro-OH
- Boc-Pro-OH
- Hydrogeno-(S)-pyrrolidine-1,2-dicarboxylate de 1-(tert-butyle)
- L-N-Boc-proline
- N-(t-Butoxycarbonyl)proline
- N-(tert-Butoxycarbonyl)-(S)-proline
- N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
- N-(tert-Butoxycarbonyl)-L-proline
- N-(tert-Butoxycarbonyl)proline
- N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
- N-(tert-Butyloxycarbonyl)-L-proline
- N-Boc-(S)-proline
- N-Boc-<span class="text-smallcaps">L</span>-proline
- N-Boc-L-proline
- N-[(1,1-Dimethylethoxy)carbonyl]-(S)-proline
- N-alpha-tert-BOC-L-proline
- Nsc 164660
- hidrogeno-(S)-pirrolidina-1,2-dicarboxilato de 1-(terc-butilo)
- tert-Butoxycarbonyl-L-proline
- tert-Butyloxycarbonyl-L-proline
- trans-N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
- BOC-L-PROLINE-OH
- N-ALPHA-T-BUTOXYCARBONYL-L-PROLINE
- BOC-L-PRO
- N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PROLINE
- N-T-BOC-L-PROLINE
- BOC-L-PROLINE
- N-ALPHA-T-BOC-L-PROLINE
- BOC-PRO
- N-T-BUTOXYCARBONYL-L-PROLINE
- BOC-PYRD(2)-OH
- N-(TERT-BUTOXYCARBONYL)-L-PROILNE
- N-ALPHA-T-BUTOXYCARBONYL-L-PYRROLIDINE-2-CARBOXYLIC ACID
- See more synonyms
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Found 13 products.
N-(tert-Butoxycarbonyl)-L-proline
CAS:Formula:C10H17NO4Purity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:215.25N-Boc-L-proline, 99%
CAS:N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV). This Thermo Scientific Chemicals brand prod
Formula:C10H17NO4Purity:99%Color and Shape:Crystals or powder or crystalline powder, WhiteMolecular weight:215.25Boc-Pro-OH
CAS:Bachem ID: 4000220.
Formula:C10H17NO4Purity:> 99%Color and Shape:WhiteMolecular weight:215.25N-(tert-Butoxycarbonyl)-L-proline
CAS:Formula:C10H17NO4Purity:97%Color and Shape:SolidMolecular weight:215.2463(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protected
CAS:(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protectedFormula:C10H17NO4Purity:99%Color and Shape: white solidMolecular weight:215.25g/molBoc-Pro-OH
CAS:M03314 - Boc-Pro-OH
Formula:C10H17NO4Purity:97%Color and Shape:SolidMolecular weight:215.249N-Boc-L-proline
CAS:Controlled ProductApplications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);Formula:C10H17NO4Color and Shape:NeatMolecular weight:215.25BOC-L-Proline extrapure, 99%
CAS:Formula:C10H17NO4Purity:min. 99%Color and Shape:White, Crystalline powderMolecular weight:215.30N-Boc-L-proline
CAS:N-Boc-L-proline is a proline derivative that has been synthesized as a drug candidate for cancer treatment. It has been shown to inhibit the activity of the enzyme, buserelin, which is involved in the synthesis of histamine and other substances. N-Boc-L-proline has also been shown to cause neuronal death by hydrogen bond formation with nitrogen nucleophiles in the brain, leading to apoptosis. The chromatographic method was used to analyze reaction products from N-Boc-L-proline with sodium carbonate. This compound has solubility data and an intramolecular hydrogen bond that can be detected by nmr spectroscopy. Trifluoroacetic acid was used as a solvent for this experiment.Formula:C10H17NO4Purity:Min. 95%Color and Shape:White PowderMolecular weight:215.25 g/molBoc-Pro-OH
CAS:Boc-Pro-OH is a synthetic amino acid that is used in the preparation of samples for gas chromatography. Boc-Pro-OH has antiinflammatory activity, and can be used to treat cancer. It is also used as an intermediate in the synthesis of amides, which are important in pharmaceuticals. Boc-Pro-OH is soluble in water and carbonate buffer solutions, but insoluble in ethanol. The chemical structure of this molecule is unusual because it contains a Boc group.
Formula:C10H17NO4Purity:Min. 95%Molecular weight:215.25 g/mol
