CAS 15775-74-3

PROGESTERONE-2,2,4,6,6,17ALPHA,21,21,21-D9

Description:

Progesterone-2,2,4,6,6,17alpha,21,21,21-D9, with the CAS number 15775-74-3, is a synthetic derivative of the natural hormone progesterone. This compound is characterized by its structural modifications that include deuterium labeling, which enhances its stability and alters its metabolic pathways. It is primarily used in research settings to study hormonal functions and mechanisms, particularly in reproductive biology and endocrinology. The presence of deuterium isotopes can improve the compound's pharmacokinetic properties, making it useful in tracing studies and metabolic experiments. As a steroid hormone, it plays a crucial role in regulating various physiological processes, including the menstrual cycle, pregnancy, and embryogenesis. Its activity is mediated through binding to progesterone receptors, influencing gene expression and cellular responses. Overall, this compound serves as a valuable tool in both clinical and laboratory research, contributing to the understanding of hormonal regulation and potential therapeutic applications.

Formula: C₂₁H₂₁D₉O₂

Progesterone-d9

CAS: 15775-74-3

Formula: C₂₁H₂₁D₉O₂

Color and Shape: White To Off-White Solid

Molecular weight: 323.52

Ref: 4Z-P-321

Progesterone-2,2,4,6,6,17α,21,21,21-d9

CAS: 15775-74-3

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 323.52

Ref: 3U-D5385

Progesterone D9 100 µg/mL in Acetonitrile

Controlled Product

CAS: 15775-74-3

Formula: C₂₁H₉H₂₁O₂

Color and Shape: Single Solution

Molecular weight: 323.52

Ref: 04-A16342010AL-100

Progesterone-d9

Controlled Product

CAS: 15775-74-3

Applications Steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),

Formula: C₂₁₂H₉H₂₁O₂

Color and Shape: Off-White To Light Yellow

Molecular weight: 323.52

Ref: TR-P755902

Progesterone-d9

Controlled Product

CAS: 15775-74-3

Progesterone-d9 is a compound that is used in the diagnosis of adrenocortical carcinoma. It can be extracted from the serum of patients with this cancer using an acetate extraction technique. Progesterone-d9 has been shown to be a useful biomarker for short-term exposure to water contaminated with nomegestrol acetate, and it has also been shown to be a useful tool for wastewater treatment. The use of Progesterone-d9 as a biomarker is limited by its instability in human serum and its susceptibility to matrix effects. This compound can be analyzed by liquid chromatography mass spectrometry (LC-MS/MS) methods, which are sensitive and specific. A drawback of this analytical method is that it requires extensive sample preparation.
The LC-MS/MS method can also be used to measure prosteroid levels, which have been found to correlate with levels of camp in humans.

Formula: C₂₁H₂₁O₂D₉

Purity: Min. 95%

Color and Shape: Off-White To Yellow Solid

Molecular weight: 323.51 g/mol

Ref: 3D-FP170246

Progesterone-d9

CAS: 15775-74-3

Formula: C₂₁H₂₁D₉O₂

Color and Shape: Solid

Molecular weight: 323.5172

Ref: IN-DA00AB2Z