CAS 157837-31-5

3-(1,3-OXAZOL-5-YL)ANILINE

Description:

3-(1,3-Oxazol-5-yl)aniline, with the CAS number 157837-31-5, is an organic compound characterized by the presence of both an aniline and an oxazole functional group. The oxazole ring, a five-membered heterocycle containing nitrogen and oxygen, contributes to the compound's unique chemical properties, including potential biological activity. This compound typically appears as a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino group in the aniline structure. Its molecular structure suggests potential applications in pharmaceuticals, agrochemicals, or as a building block in organic synthesis. The presence of the oxazole moiety may impart specific reactivity or interaction with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's stability and reactivity can be influenced by factors such as pH and the presence of other functional groups in a reaction environment. As with many organic compounds, safety data should be consulted for handling and usage guidelines.

Formula: C₉H₈N₂O

InChI: InChI=1/C9H8N2O/c10-8-3-1-2-7(4-8)9-5-11-6-12-9/h1-6H,10H2

SMILES: c1cc(cc(c1)N)c1cnco1

Synonyms:

• 5-(3-Aminophenyl)Oxazole
• Buttpark 43\57-51

3-(1,3-Oxazol-5-yl)aniline

CAS: 157837-31-5

Formula: C₉H₈N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 160.1726

Ref: IN-DA001PR9

3-(1,3-Oxazol-5-yl)aniline

CAS: 157837-31-5

3-(1,3-Oxazol-5-yl)aniline

Purity: ≥95%

Color and Shape: Powder

Molecular weight: 160.17g/mol

Ref: 54-OR29046

5-(3-Aminophenyl)oxazole

CAS: 157837-31-5

Formula: C₉H₈N₂O

Purity: 95%

Color and Shape: Beige powder

Molecular weight: 160.176

Ref: 10-F017209

3-(1,3-oxazol-5-yl)aniline

CAS: 157837-31-5

3-(1,3-Oxazol-5-yl)aniline is an inhibitor of the enzyme phosphoglycerate dehydrogenase (PGDH), which catalyzes the oxidation of 2-phosphoglycerate to 3-phosphoglycerate. It binds to PGDH and slows down the formation of 3-phosphoglycerate, which inhibits the production of ATP. The binding site for 3-(1,3-oxazol-5-yl)aniline has been determined by X-ray crystallography and affinity measurements to be near a conserved amino acid residue in the active site. This inhibition prevents cancer cells from growing and dividing. 3-(1,3-Oxazol-5-yl)aniline has been shown to inhibit breast cancer cells in vitro with high affinity.

Formula: C₉H₈N₂O

Purity: Min. 95%

Molecular weight: 160.17 g/mol

Ref: 3D-HGA83731