CAS 1580-71-8
:amiperone
Description:
Amiperone, with the CAS number 1580-71-8, is a chemical compound classified as an antipsychotic medication. It belongs to the butyrophenone class and is primarily used in the treatment of schizophrenia and other psychotic disorders. The compound exhibits a complex structure that includes a piperidine ring, which contributes to its pharmacological activity. Amiperone functions as a dopamine antagonist, particularly targeting D2 receptors, which plays a crucial role in its therapeutic effects. Additionally, it may have effects on serotonin receptors, further influencing mood and behavior. The substance is known for its sedative properties and can help manage symptoms such as hallucinations and delusions. However, like many antipsychotics, amiperone may be associated with side effects, including extrapyramidal symptoms and metabolic changes. Its pharmacokinetics involve oral administration, with a variable absorption profile, and it is metabolized in the liver. Overall, amiperone represents a significant option in the pharmacotherapy of severe mental health conditions, although its use must be carefully monitored.
Formula:C24H28ClFN2O2
InChI:InChI=1/C24H28ClFN2O2/c1-27(2)23(30)24(19-7-9-20(25)10-8-19)13-16-28(17-14-24)15-3-4-22(29)18-5-11-21(26)12-6-18/h5-12H,3-4,13-17H2,1-2H3
Synonyms:- NSC 170979
- 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethylpiperidine-4-carboxamide
- Paraperidine
- R 2962
- Isonipecotamide, 4-(p-chlorophenyl)-1-(3-(p-fluorobenzoyl)propyl)-N,N-dimethyl-
- BRN 0501454
- UNII-FTX5V7543O
- 4-(p-Chlorophenyl)-1-(3-(p-fluorobenzoyl)propyl)-N,N-dimethylisonipecotamide
- Amiperonum [INN-Latin]
- Amiperona [INN-Spanish]
- Amiperone
- Amiperona
- Amiperone [INN]
- 4-(4-Chlorophenyl)-4-(dimethylaminocarbonyl)-1-(3-(4-fluorobenzoyl)propyl)piperidine
- Amiperonum
- 5-22-02-00498 (Beilstein Handbook Reference)
- Paraperidide
- 4-Piperidinecarboxamide, 4-(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-N,N-dimethyl- (9CI)
- 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-keto-butyl]-N,N-dimethyl-isonipecotamide
- 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxo-butyl]-N,N-dimethyl-piperidine-4-carboxamide
- N,N-Dimethyl-4-(p-chlorophenyl)-1-[3-(p-fluorobenzoyl)propyl]-4-piperidinecarboxamide
- 4-Piperidinecarboxamide, 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-N,N-dimethyl-
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