CAS 158062-71-6

4-Trifluoromethylnicotinamide

Description:

4-Trifluoromethylnicotinamide is a chemical compound characterized by the presence of a nicotinamide structure, which is a derivative of niacin (vitamin B3). The compound features a trifluoromethyl group (-CF3) at the 4-position of the pyridine ring, which significantly influences its chemical properties and biological activity. This substitution enhances lipophilicity and can affect the compound's interaction with biological targets. 4-Trifluoromethylnicotinamide is typically a white to off-white solid and is soluble in organic solvents, reflecting its polar and non-polar characteristics. It is often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to modulate biological pathways. The trifluoromethyl group is known to impart unique electronic properties, making this compound of interest in various chemical and biological research fields. Safety data and handling precautions should be observed, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₇H₅F₃N₂O

InChI: InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)

InChI key: InChIKey=JUIWZYBJXUPIKF-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C(C(N)=O)=CN=CC1

Synonyms:

• 3-Pyridinecarboxamide, 4-(trifluoromethyl)-
• 4-(Trifluoromethyl)nicotinamide
• 4-Trifluoromethyl-3-Pyridinecarboxamide
• 4-Trifluoromethylnicotinamide
• Trifluoromethylpyridinecarboxamide

3-​Pyridinecarboxamide, 4-​(trifluoromethyl)​-

CAS: 158062-71-6

Formula: C₇H₅F₃N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 190.1226

Ref: IN-DA001PXW

4-(Trifluoromethyl)nicotinamide

CAS: 158062-71-6

4-(Trifluoromethyl)nicotinamide

Formula: C₇H₅F₃N₂O

Purity: 95

Color and Shape: white solid

Molecular weight: 190.12g/mol

Ref: 54-PC10153

4-Trifluoromethylnicotinamide

CAS: 158062-71-6

Formula: C₇H₅F₃N₂O

Color and Shape: Neat

Molecular weight: 190.12

Ref: 04-C17845700

4-Trifluoromethylnicotinamide 100 µg/mL in Acetonitrile

CAS: 158062-71-6

Formula: C₇H₅F₃N₂O

Color and Shape: Single Solution

Molecular weight: 190.12

Ref: 04-A17845700AL-100

4-(Trifluoromethyl)nicotinamide

Controlled Product

CAS: 158062-71-6

Applications 4-(Trifluoromethyl)nicotinamide (TFNA-AM) is a metabolite of Flonicamid (F405710); a novel insecticide with rapid inhibitory effect against aphid feeding.
References Chen, G., et al.: Sepu, 30, 555 (2012); Morita, M., et al.: Pest. Manag. Sci.,63, 969 (2007); Sabatino, L., et al.: Food. Additive. Contamin., 6, 11 (2013)

Formula: C₇H₅F₃N₂O

Color and Shape: Off-White

Molecular weight: 190.12

Ref: TR-T791315

4-Trifluoromethylnicotinamide

CAS: 158062-71-6

Formula: C₇H₅F₃N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 190.125

Ref: 10-F023451