CAS 1580889-36-6

Tolvaptan Impurity 26

CAS: 1580889-36-6

Formula: C₄₂H₃₆ClN₃O₅

Color and Shape: White To Off-White Solid

Molecular weight: 698.22

Ref: 4Z-T-6931

Dehydroxy-(2-methyl-4-(2-methylbenzamido)benzoate) Tolvaptan

Controlled Product

CAS: 1580889-36-6

Applications Dehydroxy-(2-methyl-4-(2-methylbenzamido)benzoate) Tolvaptan is the impurity of the drug Tolvaptan (T536650), which is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);

Formula: C₄₂H₃₆ClN₃O₅

Color and Shape: Neat

Molecular weight: 698.205

Ref: TR-D230653

Tolvaptan Impurity 46

CAS: 1580889-36-6

Formula: C₄₂H₃₆ClN₃O₅

Molecular weight: 698.2

Ref: ST-EA-CP-T26045