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CAS 1582205-90-0: Immunoglobulin G, anti-(human calcitonin gene-related peptide receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimer
Description:Immunoglobulin G (IgG) is a type of antibody that plays a crucial role in the immune response by identifying and neutralizing pathogens such as bacteria and viruses. The specific substance you mentioned, "Immunoglobulin G, anti-(human calcitonin gene-related peptide receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimer," is a dimeric form of IgG that targets the human calcitonin gene-related peptide receptor (CGRP receptor). This receptor is involved in various physiological processes, including pain modulation and vasodilation. The dimeric structure indicates that two antibody units are linked via disulfide bonds, enhancing its stability and functionality. This monoclonal antibody is engineered for specificity and affinity towards the CGRP receptor, making it valuable in therapeutic applications, particularly in the treatment of migraine and other related conditions. Its characteristics include high specificity, potential for reduced off-target effects, and the ability to elicit a robust immune response, which are essential for its efficacy in clinical settings.
Formula:Unspecified
- Synonyms:
- AMG 334
- Erenumab-aooe
- Erenumab
- Immunoglobulin G2-lambda, anti-(human calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor; calcitonin receptor-like receptor); human monoclonal antibody: γ2 heavy chain (1-456) [human VH (IGHV3-30*03-(IGHD)-IGHJ3*01) (94%) [8.8.23] (1-130)-IGHG2*01 (131-456)] (144-215′)disulfide with lambda light chain (1′-216′) [human V-LAMBDA (IGLV1-51*01IGLJ2*01)(98%) [8.3.11] (1′-110′) -IGLC1*02 (111′-216′)] dimer (232232′′:233-233′′:236-236′′:239-239′′)-tetrakisdisulfide
- Immunoglobulin G, anti-(human calcitonin gene-related peptide receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimer
Brand | Product data | Purity | Price range | Estimated delivery |
---|---|---|---|---|
![]() | Erenumab REF: TM-T76874CAS: 1582205-90-0 | 99.43% (SEC-HPLC) - > 95% | 202.00 €~842.00 € | Fri 14 Mar 25 |
![]() | Erenumab REF: 3D-CLA1433CAS: 1582205-90-0 | - - - | To inquire | Mon 24 Mar 25 |
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Erenumab
Ref: TM-T76874
1mg | 202.00 € | ||
5mg | 535.00 € | ||
10mg | 842.00 € |
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Ref: 3D-CLA1433
Undefined size | To inquire |