CAS 158257-40-0

FMOC-STA-OH

Description:

FMOC-STA-OH, or 9-fluorenylmethoxycarbonyl-Serine, is a chemical compound commonly used in peptide synthesis as a protective group for the amino acid serine. The FMOC (9-fluorenylmethoxycarbonyl) group is favored for its stability under basic conditions and ease of removal under mild acidic conditions, making it ideal for sequential peptide synthesis. The presence of the serine moiety imparts specific characteristics, such as the ability to participate in hydrogen bonding and contribute to the overall polarity of the peptide chain. FMOC-STA-OH is typically utilized in solid-phase peptide synthesis (SPPS), where it helps in the selective protection of the amino group while allowing for the coupling of other amino acids. The compound is generally handled with standard laboratory precautions, as it may pose risks associated with chemical exposure. Its applications extend beyond peptide synthesis, potentially influencing fields such as drug development and biochemistry, where precise control over amino acid functionality is crucial.

Formula: C₂₃H₂₇NO₅

Synonyms:

• Fmoc-(S,S)Sta-Oh
• Fmoc-Sta(3S,4S)-Oh
• Fmoc-Statine
• Fmoc-Leu-Statine
• Fmoc-(3S,4S)-4-Amino-3-Hydroxy-6-Methyl Heptanoic Acid
• Fmoc-(3S,4S)-Sta-Oh
• (3S,4S)-4-(Fmoc-Amino)-3-Hydroxy-6-Methylheptanoic Acid
• FMOC-STA-OH

Fmoc-statine

CAS: 158257-40-0

Bachem ID: 4100293.

Formula: C₂₃H₂₇NO₅

Purity: 97.6%

Molecular weight: 397.47

Ref: 01-4100293

Heptanoic acid, 4-​[[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​amino]​-​3-​hydroxy-​6-​methyl-​, (3S,​4S)​-

CAS: 158257-40-0

Formula: C₂₃H₂₇NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 397.4642

Ref: IN-DA001Q2S

(3S,4S)-4-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-3-Hydroxy-6-Methylheptanoic Acid

CAS: 158257-40-0

(3S,4S)-4-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-3-Hydroxy-6-Methylheptanoic Acid

Purity: 98%

Molecular weight: 397.46g/mol

Ref: 54-OR1008143

N-FMOC-L-Statine

CAS: 158257-40-0

Purity: 95.0%

Color and Shape: Solid, White powder

Molecular weight: 397.47100830078125

Ref: 10-F080136

Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid

CAS: 158257-40-0

Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid is a pharmacokinetic drug that is under investigation for prostate cancer. It has been shown to inhibit the growth of prostate carcinoma cells and reduce the expression of prostate specific antigen (PSA) in vivo. Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid has also been used in bioconjugate chemistry to produce a prodrug that can be taken orally. This prodrug is activated by viral proteases in the stomach, leading to an increase in cytotoxicity against HIV virus and other retroviruses. Fmoc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid has also been shown to inhibit the production of human serum erythropoietin (EPO).

Formula: C₂₃H₂₇NO₅

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 397.46 g/mol

Ref: 3D-FF47358