CAS 15826-37-6

cromolyn sodium

Description:

Cromolyn sodium, with the CAS number 15826-37-6, is a medication primarily used as an anti-inflammatory agent and mast cell stabilizer. It is commonly employed in the management of asthma, allergic rhinitis, and other allergic conditions. Cromolyn sodium works by preventing the release of inflammatory mediators from mast cells, thereby reducing bronchoconstriction and inflammation. The substance is typically administered via inhalation, nasal spray, or eye drops, depending on the condition being treated. In its pure form, cromolyn sodium is a white to off-white crystalline powder that is soluble in water and has a relatively low molecular weight. It is stable under normal conditions but should be stored away from light and moisture to maintain its efficacy. Cromolyn sodium is generally well-tolerated, with a low incidence of side effects, making it a preferred choice for long-term management of allergic conditions, especially in pediatric populations.

Formula: C₂₃H₁₆O₁₁·2Na

InChI: InChI=1S/C23H16O11.2Na/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;

InChI key: InChIKey=AIXRIMKZFKFIAF-UHFFFAOYSA-N

SMILES: O(CC(COC1=C2C(OC(C(O)=O)=CC2=O)=CC=C1)O)C3=C4C(OC(C(O)=O)=CC4=O)=CC=C3.[Na]

Synonyms:

• 1,3-Bis(2-carboxychromon-7-yloxy)-2-hydroxypropane disodium salt
• 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, disodium salt
• 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, sodium salt (1:2)
• 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxytrimethylene)dioxy]bis[4-oxo-, disodium salt
• 5,5'-[(2-hidroxitrimetilen)bis(oxi)]bis[4-oxo-4H-1-benzopirano-2-carboxilato] de disodio
• 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylic acid)
• 5,5'-[(2-hydroxytrimethylene)bis(oxy)]bis[4-oxo-4H-1-benzopyranne-2-carboxylate] de disodium
• Aarane
• Alercrom
• Alerion
• Allergocrom
• Altoderm
• Colimune
• Crolom
• Cromoglicate Sodium
• Cromoglycate
• Cromoglycate disodium
• Cromoglycate sodium
• Cromolyn disodium salt
• Cromovet
• Dinatrium-5,5'-[(2-hydroxytrimethylen)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylat]
• Disodium 1,3-bis(2-carboxy-5-chromonyloxy)-2-propanol
• Disodium 1,3-bis(2-carboxychromon-5-yloxy)-2-hydroxypropane
• Disodium 1,3-bis(2-carboxychromon-5-yloxy)propan-2-ol
• Disodium 5,5'-[(2-hydroxytrimethylene)dioxy]bis[4-oxo-4H-1-benzopyran-2-carboxylate]
• Disodium 5,5-[(2-hydroxytrimethylene)-bis-(oxy)]-bis[4-oxo--1-benzopyran-2
• Disodium Cromoglicate
• Disodium chromoglycate
• Disodium cromoglycate
• Dncg
• Dscg
• Fisonair
• Fivent
• Fpl 670
• Gastrocrom
• Gastrofrenal
• Inostral
• Intal
• Intal Forte
• Intal UD
• Introl
• Irtan
• Lomudal
• Lomupren
• Lomusol
• Lomuspray
• Nalcrom
• Nalcron
• NasalCrom
• Nasmil
• Nasotal
• Opticrom
• Rynacrom
• Sodium Cromoglicate
• Sodium Cromoylycate
• Sodium chromoglycate
• Sodium cromoglycate
• Sodium cromolyn
• Sofro
• Vividrin
• [6-[2-Hydroxy-3-(4-Oxo-2-Sodiooxycarbonyl-Chromen-6-Yl)Oxy-Propoxy]-4-Oxo-Chromene-2-Carbonyl]Oxysodium
• disodium 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylate)
• disodium 5,5'-[(2-hydroxytrimethylene)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylate]

Cromolyn sodium salt, 98%

CAS: 15826-37-6

Mast cell stabilizer that prevents release of histamine from mast cells

Formula: C₂₃H₁₄Na₂O₁₁

Purity: 98%

Color and Shape: White to pale yellow, Powder

Molecular weight: 512.33

Ref: 02-J65122

SODIUM CROMOGLICATE FOR SYSTEM SUITABILITY CRS

CAS: 15826-37-6

SODIUM CROMOGLICATE FOR SYSTEM SUITABILITY CRS

Formula: C₂₃H₁₄Na₂O₁₁

Molecular weight: 512.3302

Ref: 41-Y0001300

SODIUM CROMOGLICATE CRS

CAS: 15826-37-6

SODIUM CROMOGLICATE CRS

Formula: C₂₃H₁₄Na₂O₁₁

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 512.3302

Ref: 41-S0750000

Cromolyn Sodium

CAS: 15826-37-6

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₂₃H₁₄Na₂O₁₁

Color and Shape: White Crystalline Powder

Molecular weight: 512.33 g/mol

Ref: 45-1150502

4H-1-BENZOPYRAN-2-CARBOXYLICACID, 5,5'-[(2-HYDROXY-1,3-PROPANEDIYL)BIS(OXY)]BIS[4-OXO-, SODIUM SALT (1:2)

CAS: 15826-37-6

Formula: C₂₃H₁₄Na₂O₁₁

Purity: 95%

Color and Shape: Solid

Molecular weight: 512.3302

Ref: IN-DA003UC5

Cromolyn sodium

CAS: 15826-37-6

Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.

Formula: C₂₃H₁₄Na₂O₁₁

Purity: 99.4% - 99.95%

Color and Shape: Colorless Crystals From Ethanol + Ether White Crystalline Powder

Molecular weight: 512.33

Ref: TM-T1260

Cromolyn sodium salt

CAS: 15826-37-6

Formula: C₂₃H₁₄Na₂O₁₁

Purity: ≥ 98.0% (anhydrous)

Color and Shape: White to light-yellow powder

Molecular weight: 512.33

Ref: 7W-GP8420

Cromolyn sodium

CAS: 15826-37-6

Cromolyn sodium

Purity: ≥98%

Molecular weight: 512.33g/mol

Ref: 54-BUP19568

Sodium Cromoglycate

CAS: 15826-37-6

Formula: C₂₃H₁₄O₁₁·2Na

Color and Shape: White To Off-White Solid

Molecular weight: 466.36 2 22.99

Ref: 4Z-C-107001

Sodium Cromoglycate

CAS: 15826-37-6

Sodium Cromoglycate

Purity: 99%

Molecular weight: 512.33g/mol

Ref: 54-OR1015014

Cromolyn Disodium Salt

CAS: 15826-37-6

Formula: C₂₃H₁₄Na₂O₁₁

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 512.33

Ref: 3B-C2521

Sodium Cromoglicate

Controlled Product

CAS: 15826-37-6

Formula: C₂₃H₁₄O₁₁Na

Color and Shape: Neat

Molecular weight: 512.33

Ref: 86-MM0039.00

Cromolyn Disodium Salt

Controlled Product

CAS: 15826-37-6

Stability Hygroscopyc
Applications Chromone complex which blocks mast cell degranulation.
References Ashton, M.J., et al.: Toxicol. Appl. Pharmacol., 26, 319 (1973), Friday, G.A., et al.: Am. J. Ophthalmol., 95, 169 (1983),

Formula: C₂₃H₁₄O₁₁·2Na

Color and Shape: Neat

Molecular weight: 512.33

Ref: TR-C815000

Cromolyn-d5 Disodium Salt

Controlled Product

CAS: 15826-37-6

Stability Hygroscopic
Applications Chromone complex which blocks mast cell degranulation.
References Ashton, M.J., et al.: Toxicol. Appl. Pharmacol., 26, 319 (1973), Friday, G.A., et al.: Am. J. Ophthalmol., 95, 169 (1983)

Formula: C₂₃H₉D₅Na₂O₁₁

Color and Shape: Neat

Molecular weight: 517.36

Ref: TR-C815002

Cromolyn disodium

CAS: 15826-37-6

Cromolyn disodium salt is a drug that belongs to the class of drugs called cromoglycates. It is used to treat asthma and chronic cough. Cromolyn binds to the protein guanylate cyclase, which inhibits the synthesis of cell signaling molecules called cyclic guanosine monophosphate (cGMP). It also has a direct effect on mast cells, preventing histamine release and stabilizing the cell membrane. Cromolyn also blocks the action of histamine-releasing factors such as acetylcholine, prostaglandins, and leukotrienes. This drug has been shown to be effective in treating both asthma and chronic cough when given in conjunction with other drugs such as benzalkonium chloride or budesonide.

Formula: C₂₃H₁₆O₁₁•Na₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 514.35 g/mol

Ref: 3D-FC20587