CAS 1584149-34-7

Rosuvastatin 3S, 5S-isomer

Description:

Rosuvastatin 3S, 5S-isomer, identified by CAS number 1584149-34-7, is a specific stereoisomer of rosuvastatin, a member of the statin class of drugs primarily used to lower cholesterol levels in the blood. This compound exhibits a high affinity for inhibiting HMG-CoA reductase, an enzyme crucial in the cholesterol biosynthesis pathway. The 3S, 5S configuration indicates the specific spatial arrangement of atoms in the molecule, which is essential for its biological activity. Rosuvastatin is characterized by its potent lipid-lowering effects, making it effective in reducing low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol. Additionally, it has anti-inflammatory properties and may provide cardiovascular benefits beyond cholesterol management. The pharmacokinetics of this isomer include good oral bioavailability and a relatively long half-life, allowing for once-daily dosing. As with other statins, potential side effects may include muscle pain, liver enzyme elevation, and gastrointestinal disturbances, necessitating monitoring during therapy.

Formula: C₂₂H₂₈FN₃O₆S

Synonyms:

• Rosuvastatin 3S, 5S-isomer
• (3S,5S)-Rosuvastatin Calcium
• (3S,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
• (3S,5S)-Rosuvastatin
• Rosuvastatin 3S,5S-Isomer Sodium (acid)
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3S,5S,6E)-
• (3S,5S)-Rosuvastatin Calcium Q: What is the CAS Number of
• Rosuvastatin isomer-19
• (3S,5S)-Rosuvastatin Calcium Q: What is the storage condition of
• (3S,5S)-Rosuvastatin CalciumQ: What is

(3S,5S)-Rosuvastatin Sodium Salt

CAS: 1584149-34-7

Formula: C₂₂H₂₇FN₃O₆S·Na

Color and Shape: White To Off-White Solid

Molecular weight: 480.53 22.99

Ref: 4Z-R-0919

(3S,5S)-Rosuvastatin calcium

CAS: 1584149-34-7

Rosuvastatin calcium is a statin drug that belongs to the group of HMG-CoA reductase inhibitors. Rosuvastatin is a racemic mixture of 3S,5S and 3R,5R stereoisomers and has been shown to have cholesterol-lowering effect in humans. The sample solution was prepared by dissolving rosuvastatin calcium in methanol and then diluting it with water. The calibration curve was performed using solutions of substances at different concentrations and injecting them into the liquid chromatograph. After running for 2 minutes, the detection wavelength and detection method were used to measure the concentration of rosuvastatin. The result was recorded as mg/mL (molecules per milliliter).

Formula: C₂₂H₂₇FN₃O₆SCa

Purity: Min. 95%

Molecular weight: 480.53 g/mol

Ref: 3D-IR171092