CAS 1584647-27-7

BMS 986115

Controlled Product

CAS: 1584647-27-7

BMS 986115 is a secretase inhibitor that inhibits the amyloid-β (Aβ) pathway, which may be responsible for the development of Alzheimer's disease. BMS 986115 has been shown to have anti-cancer effects in preclinical models, blocking constitutive activation of β-catenin and suppressing tumour growth. In addition, BMS 986115 has been shown to be effective against solid tumours and life-threatening desmoid tumours. It has also been shown to be well tolerated with minimal toxicity in preclinical models.

Formula: C₂₆H₂₅F₇N₄O₃

Purity: Min. 95%

Molecular weight: 574.5 g/mol

Ref: 3D-JNC64727

Notch inhibitor 1

CAS: 1584647-27-7

Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.

Formula: C₂₆H₂₅F₇N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 574.49

Ref: TM-T16341