CAS 158493-17-5

(4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-indeno[5,4-f]quinolin-2-one

Description:

The chemical substance with the name "(4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-indeno[5,4-f]quinolin-2-one" and CAS number "158493-17-5" is a complex organic compound characterized by its intricate polycyclic structure, which includes a quinoline moiety. This compound features multiple chiral centers, indicating that it can exist in various stereoisomeric forms, which may influence its biological activity and interactions. The presence of a dimethylhexyl substituent suggests potential lipophilicity, which could affect its solubility and permeability in biological systems. Additionally, the hexadecahydro framework indicates a saturated structure, which may contribute to its stability and resistance to oxidation. Such compounds are often studied for their potential applications in pharmaceuticals, agrochemicals, or as intermediates in organic synthesis. Understanding its properties, including melting point, boiling point, and reactivity, would require specific experimental data or computational modeling to predict its behavior in various environments.

Formula: C₂₈H₄₉NO

InChI: InChI=1/C28H49NO/c1-18(2)9-8-10-19(3)21-11-12-22-26-20(4)17-24-28(6,16-14-25(30)29(24)7)23(26)13-15-27(21,22)5/h18-24,26H,8-17H2,1-7H3

InChI key: InChIKey=XUTZDXHKQDPUMA-MVJJLJOTSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])([C@@H](C)C[C@]1(N(C)C(=O)CC2)[H])[H])[H]

Synonyms:

• 2H-Indeno[5,4-f]quinolin-2-one, 7-[(1R)-1,5-dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-, (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-
• 4-Azacholestan-3-one, 4,7-dimethyl-, (5α,7β)-
• MK 386
• 2H-Indeno[5,4-f]quinolin-2-one, 7-(1,5-dimethylhexyl)hexadecahydro-1,4a,6a,10-tetramethyl-, [4aR-[4aα,4bβ,6aα,7α(R*),9aβ,9bα,10α,11aβ]]-
• (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-indeno[5,4-f]quinolin-2-one

MK 386

Controlled Product

CAS: 158493-17-5

Formula: C₂₈H₄₉NO

Color and Shape: Neat

Molecular weight: 415.695

Ref: TR-M425163

MK 386

CAS: 158493-17-5

MK 386 is a thiazolidinedione that has been shown to decrease insulin resistance and improve insulin sensitivity. It also decreases the production of sulfurous compounds in the body, which have been shown to be responsible for hair loss. MK 386 is a sulfate prodrug that is converted to its active form by sulfotransferases, enzymes found in many tissues. MK 386 has been shown to normalize follicle size and increase hair growth in patients with alopecia. The uptake of MK 386 is oriented towards the insulin-sensitive tissue such as muscle cells, adipocytes, and liver cells, while finasteride blocks the receptor that responds to testosterone.

Formula: C₂₈H₄₉NO

Purity: Min. 95%

Molecular weight: 415.7 g/mol

Ref: 3D-IGA49317

MK-386

CAS: 158493-17-5

MK-386 is a potent and selective inhibitor of human type-1 5alpha-reductase.

Formula: C₂₈H₄₉NO

Color and Shape: Solid

Molecular weight: 415.69

Ref: TM-T28058