CAS 158584-09-9

7-methoxycoumarin-4-acetyl-arg-pro-*lys-pro-val-G

Description:

7-Methoxycoumarin-4-acetyl-arg-pro-*lys-pro-val-G, identified by its CAS number 158584-09-9, is a synthetic compound that combines a coumarin moiety with a peptide sequence. The coumarin structure is known for its fluorescent properties, making it useful in various biochemical applications, including as a fluorescent probe in cellular imaging. The presence of the acetyl group enhances its solubility and stability, while the peptide sequence, which includes amino acids such as arginine, proline, lysine, and valine, may impart specific biological activities or facilitate interactions with biological targets. This compound is often studied in the context of drug development and molecular biology due to its potential therapeutic applications and ability to modulate biological processes. Its unique structure allows for the exploration of its pharmacological properties, including its efficacy and mechanism of action in various biological systems. Overall, 7-methoxycoumarin-4-acetyl-arg-pro-*lys-pro-val-G represents a versatile compound with significant implications in research and medicine.

Formula: C₇₈H₁₁₀N₂₂O₂₀

InChI: InChI=1/C78H110N22O20/c1-5-16-53(68(106)95-58(37-45-42-88-50-18-7-6-17-48(45)50)71(109)92-54(21-12-33-86-77(81)82)69(107)90-52(67(80)105)19-9-11-32-85-51-28-25-46(99(115)116)40-61(51)100(117)118)91-70(108)55(29-30-64(102)103)93-74(112)66(43(2)3)96-73(111)60-24-15-36-98(60)76(114)57(20-8-10-31-79)94-72(110)59-23-14-35-97(59)75(113)56(22-13-34-87-78(83)84)89-63(101)38-44-39-65(104)120-62-41-47(119-4)26-27-49(44)62/h6-7,17-18,25-28,39-43,52-60,66,85,88H,5,8-16,19-24,29-38,79H2,1-4H3,(H2,80,105)(H,89,101)(H,90,107)(H,91,108)(H,92,109)(H,93,112)(H,94,110)(H,95,106)(H,96,111)(H,102,103)(H4,81,82,86)(H4,83,84,87)/t52-,53-,54-,55-,56-,57-,58-,59-,60-,66-/m0/s1

SMILES: CCC[C@@H](C(=N[C@@H](Cc1c[nH]c2ccccc12)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCCCNc1ccc(cc1N(=O)=O)N(=O)=O)C(=N)O)O)O)O)N=C([C@H](CCC(=O)O)N=C([C@H](C(C)C)N=C([C@@H]1CCCN1C(=O)[C@H](CCCCN)N=C([C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N=C(Cc1cc(=O)oc2cc(ccc12)OC)O)O)O)O)O

Synonyms:

• Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2
• Nff 3
• ((7-Methoxycoumarin-4-yl)acetyl)arginyl-prolyl-lysyl-prolyl-valyl-glutamyl-norvalyl-tryptophyl-arginyl-(2,4-dinitrophenyl)lysinamide
• Mca-arg-pro-lys-pro-val-glu-nva-trp-arg-lys(dnp)-NH2
• N2-((7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysinamide
• L-Lysinamide, N2-((7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl)-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-valyl-L-alpha-glutamyl-L-norvalyl-L-tryptophyl-L-arginyl-N6-(2,4-dinitrophenyl)-

Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂

CAS: 158584-09-9

The FRET substrate Mca-RPKPVE-Nva-WRK(Dnp) amide was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2.

Formula: C₇₈H₁₁₀N₂₂O₂₀

Purity: 96.18%

Color and Shape: Powder

Molecular weight: 1675.87

Ref: 01-4030842

MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH₂

CAS: 158584-09-9

MOCA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 is a synthetic peptide that interacts with the nicotinic acetylcholine receptor and is a potent agonist. MOCA was found to be a potent activator of the nicotinic acetylcholine receptor, as well as an inhibitor of ligand binding. The affinity for binding to the receptor was found to be high, with an inhibition constant (Ki) of 0.06 μM. It has been shown to inhibit ion channels and ligand binding in cell biology experiments. MOCA can also be used as a research tool for studying protein interactions and receptors.

Formula: C₇₈H₁₁₀N₂₂O₂₀

Purity: Min. 95%

Molecular weight: 1,675.8 g/mol

Ref: 3D-SMO-3168-V

Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt

CAS: 158584-09-9

Please enquire for more information about Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₇₈H₁₁₀N₂₂O₂₀

Purity: Min. 95%

Molecular weight: 1,675.84 g/mol

Ref: 3D-FM110916