CAS 158681-13-1: Rimonabant hydrochloride
Description:Rimonabant hydrochloride is a synthetic cannabinoid and a selective antagonist of the cannabinoid receptor type 1 (CB1). It is primarily known for its application in weight management and obesity treatment, as it works by blocking the effects of endocannabinoids that stimulate appetite. The compound is characterized by its molecular formula, which includes elements such as carbon, hydrogen, nitrogen, and chlorine. Rimonabant hydrochloride is typically presented as a white to off-white crystalline powder, soluble in organic solvents but less so in water. Its pharmacological profile indicates that it may also have effects on mood and anxiety, leading to concerns about potential psychiatric side effects. Due to these adverse effects, Rimonabant was withdrawn from the market in several countries. The substance is classified under various regulatory frameworks, and its use is restricted in many regions. Overall, Rimonabant hydrochloride exemplifies the complex interplay between cannabinoid receptors and metabolic processes, highlighting the challenges in developing safe and effective pharmacotherapies.
Formula:C22H21Cl3N4O·ClH
InChI:InChI=1S/C22H21Cl3N4O.ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15;/h5-10,13H,2-4,11-12H2,1H3,(H,27,30);1H
InChI key:InChIKey=REOYOKXLUFHOBV-UHFFFAOYSA-N
SMILES:Cl.O=C(NN1CCCCC1)C2=NN(C3=CC=C(Cl)C=C3Cl)C(C=4C=CC(Cl)=CC4)=C2C
- Synonyms:
- SR 151716A
- 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-, hydrochloride (1:1)
- Rimonabant hydrochloride
- SR 141716A
- 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-, monohydrochloride
