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CAS 158732-55-9

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escin IIa

Description:
Escin IIa, also known as aescin or escin, is a triterpenoid saponin derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is characterized by its complex structure, which includes a steroid-like backbone with sugar moieties attached. Escin IIa exhibits various pharmacological properties, including anti-inflammatory, antioxidant, and venotonic effects, making it useful in treating conditions related to venous insufficiency and edema. The substance is known to enhance capillary permeability and improve microcirculation, which contributes to its therapeutic applications. Additionally, escin IIa has been studied for its potential protective effects on the cardiovascular system. Its solubility in water is limited due to its saponin nature, which can lead to foaming in aqueous solutions. As a natural compound, escin IIa is often included in herbal remedies and dietary supplements, although its use should be approached with caution due to potential side effects and interactions with other medications. Overall, escin IIa is a notable compound in both pharmacology and herbal medicine.
Formula:C54H84O23
InChI:InChI=1/C54H84O23/c1-10-23(2)45(69)77-42-43(71-24(3)58)54(22-57)26(17-49(42,4)5)25-11-12-30-50(6)15-14-32(51(7,21-56)29(50)13-16-52(30,8)53(25,9)18-31(54)60)73-48-40(75-46-36(64)33(61)27(59)20-70-46)38(66)39(41(76-48)44(67)68)74-47-37(65)35(63)34(62)28(19-55)72-47/h10-11,26-43,46-48,55-57,59-66H,12-22H2,1-9H3,(H,67,68)/b23-10+/t26-,27+,28+,29+,30+,31+,32-,33-,34+,35-,36+,37+,38-,39-,40+,41-,42-,43-,46-,47-,48+,50-,51+,52+,53+,54-/m0/s1
Synonyms:
  • (3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->4)-[β-D-xylopyranosyl-(1->
  • 2)]-β-D-glucopyranosiduronic acid
  • 2-butenoic acid, 2-methyl-, (3β,16α,21β,22α)-22-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1-> 4)-O-[β-D-xylopyranosyl-(1->2)]-β-D-glucopyranuronosyl]oxy]-16,24,28-trihydroxyolean-12-en-21-yl ester, (2E)-
  • (3beta,16alpha,21beta,22alpha)-22-(acetyloxy)-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl beta-D-glucopyranosyl-(1->4)-[beta-D-xylopyranosyl-(1->2)]-beta-D-glucopyranosiduronic acid
  • β-D-Glucopyranosiduronic acid, (3β,4β,16α,21β,22α)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→4)-O-[β-D-xylopyranosyl-(1→2)]-
  • b-D-Glucopyranosiduronic acid, (3b,4b,16a,21b,22a)-22-(acetyloxy)-16,23,28-trihydroxy-21-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]olean-12-en-3-ylO-b-D-glucopyranosyl-(14)-O-[b-D-xylopyranosyl-(12)]-
  • AESCIN IIA
  • escin IIa
  • 82XHO27XQ8
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Found 3 products.
  • Escin IIA
    Targetmol
    + Info

    Escin IIA

    CAS:
    Escin IIA, a saponin from horse chestnut seeds, reduces acute inflammation and protects against ethanol-induced gastric lesions
    Formula:C54H84O23
    Purity:97.63%
    Color and Shape:Solid
    Molecular weight:1101.24

    Ref: TM-TN1358

  • Escin IIA
    Biopurify
    + Info

    Escin IIA

    CAS:
    Formula:C54H84O23
    Purity:95%~99%
    Molecular weight:1101.24

    Ref: BP-BP0558

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    To inquire
  • Escin Iia
    Biosynth
    + Info

    Escin Iia

    CAS:
    <p>Escin Iia is a peptide made from the extract of horse chestnut seed. It is a potent inhibitor of phosphodiesterase-4, which is responsible for degradation of cAMP in cells. Escin Iia has been shown to activate ion channels and inhibit acetylcholine esterase, which are involved in regulating neurotransmitter release at synapses. It also inhibits the binding of an antibody to its receptor, which may have applications in research and development of pharmaceuticals. Escin Iia has been used as a research tool for studying protein interactions, cell biology, pharmacology, and life science.</p>
    Formula:C54H84O23
    Purity:Min. 95%
    Molecular weight:1,101.2 g/mol

    Ref: 3D-IGA73255

    50mg
    845.00€
    100mg
    1,108.00€