CAS 158749-76-9

Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, (S)-, phosphate (1:2) (salt)

Description:

The chemical substance known as Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, (S)-, phosphate (1:2) (salt), with CAS number 158749-76-9, is a complex organic compound characterized by its specific structural components. It features a quinoline moiety, which is a bicyclic aromatic compound known for its biological activity, particularly in medicinal chemistry. The presence of the chloro group enhances its pharmacological properties, potentially influencing its interaction with biological targets. The compound also contains an ethanolamine structure, which contributes to its solubility and reactivity. As a phosphate salt, it likely exhibits enhanced stability and solubility in aqueous environments, making it suitable for various applications, including pharmaceutical formulations. The (S)- designation indicates that the compound has a specific stereochemistry, which can significantly affect its biological activity and interaction with receptors. Overall, this compound's unique combination of functional groups and stereochemistry suggests potential utility in therapeutic contexts, particularly in the development of targeted treatments.

Formula: C₁₈H₂₆ClN₃O·2H₃O₄P

InChI: InChI=1S/C18H26ClN3O.H3O4P/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H3,1,2,3,4)/t14-;/m0./s1

InChI key: InChIKey=GUEMMFXTIVHHQN-UQKRIMTDSA-N

SMILES: N([C@H](CCCN(CCO)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2.P(=O)(O)(O)O

Synonyms:

• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, (S)-, phosphate (1:2) (salt)
• (S)-(+)-Hydroxychloroquine diphosphate

(S)-(+)-Hydroxy Chloroquine-d5 Diphosphate

Controlled Product

CAS: 137433-24-0, 158749-76-9

Formula: C₁₈H₂₇D₅ClN₃O₉P₂

Color and Shape: Neat

Molecular weight: 536.89

Ref: TR-H905308

(S)-(+)-Hydroxy Chloroquine Diphosphate

Controlled Product

CAS: 158749-76-9

Formula: C₁₈H₂₆ClN₃O·2H₃O₄P

Color and Shape: Neat

Molecular weight: 531.86

Ref: TR-H905305

(S)-(+)-Hydroxy Chloroquine-d4 Diphosphate

Controlled Product

CAS: 137433-24-0, 158749-76-9, 2557418-99-0, 645406-45-7

Formula: C₁₈H₂₂D₄ClN₃O·2(H₃PO₄)

Color and Shape: Neat

Molecular weight: 535.88

Ref: TR-H905307

(S)-(+)-Hydroxy chloroquine diphosphate

CAS: 158749-76-9

(S)-(+)-Hydroxy chloroquine diphosphate is a drug that can be used to treat chronic kidney disease. It is a prodrug of hydroxychloroquine, which is also an anti-inflammatory agent. (S)-(+)-Hydroxychloroquine diphosphate has been shown to inhibit the growth of cancer cells in vitro and in vivo by inducing autophagy. This drug inhibits the tyrosine kinase receptor on cancer cells and blocks the downstream signaling pathways that lead to tumor cell proliferation. (S)-(+)-Hydroxychloroquine diphosphate has been shown to have a higher activity than hydroxychloroquine when tested against skin tumors in animals. The liposomal formulation of this drug allows for high concentrations to be achieved at the site of inflammation, making it more effective for treatment of cutaneous lesions.

Formula: C₁₈H₂₆ClN₃O

Purity: Min. 95%

Molecular weight: 335.9 g/mol

Ref: 3D-IGA74976