CAS 158751-64-5

5-Chloro-2-methoxy-N-[2-[4-methoxy-3-[[[(methylamino)thioxomethyl]amino]sulfonyl]phenyl]ethyl]benzamide

Description:

5-Chloro-2-methoxy-N-[2-[4-methoxy-3-[[[(methylamino)thioxomethyl]amino]sulfonyl]phenyl]ethyl]benzamide, with CAS number 158751-64-5, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as chloro, methoxy, thioxomethyl, and sulfonamide. This compound typically exhibits properties associated with its aromatic and heterocyclic components, contributing to its potential biological activity. It may possess solubility in organic solvents, while its polar functional groups could enhance solubility in polar solvents. The presence of the sulfonamide group suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's structure indicates it may have applications in pharmaceuticals, particularly in the development of therapeutic agents. Its stability, reactivity, and specific interactions would depend on the surrounding conditions, such as pH and temperature. As with many synthetic compounds, safety and handling precautions are essential due to potential toxicity or reactivity.

Formula: C₁₉H₂₂ClN₃O₅S₂

InChI: InChI=1S/C19H22ClN3O5S2/c1-21-19(29)23-30(25,26)17-10-12(4-6-16(17)28-3)8-9-22-18(24)14-11-13(20)5-7-15(14)27-2/h4-7,10-11H,8-9H2,1-3H3,(H,22,24)(H2,21,23,29)

InChI key: InChIKey=VXTKXGKPBOLHRY-UHFFFAOYSA-N

SMILES: S(NC(NC)=S)(=O)(=O)C1=C(OC)C=CC(CCNC(=O)C2=C(OC)C=CC(Cl)=C2)=C1

Synonyms:

• HMR 1883
• 5-Chloro-2-methoxy-N-[2-[4-methoxy-3-[[[(methylamino)thioxomethyl]amino]sulfonyl]phenyl]ethyl]benzamide
• Benzamide, 5-chloro-2-methoxy-N-[2-[4-methoxy-3-[[[(methylamino)thioxomethyl]amino]sulfonyl]phenyl]ethyl]-
• Clamikalant

Clamikalant

CAS: 158751-64-5

Clamikalant is a potent and selective inhibitor of lipoprotein lipase, which is an enzyme that plays a critical role in the metabolism of fats. It is used for inflammatory diseases such as rheumatoid arthritis or psoriasis, and it has been studied in cancer patients with metabolic disorders. Clamikalant has also shown to be effective against neurodevelopmental and cardiac arrhythmia disorders. Clamikalant binds to the active site of lipoprotein lipase by acting as a competitive inhibitor, thereby blocking the hydrolysis of triglycerides.

Formula: C₁₉H₂₂ClN₃O₅S₂

Purity: Min. 95%

Molecular weight: 472 g/mol

Ref: 3D-IGA75164

Clamikalant

CAS: 158751-64-5

Clamikalant inhibits ATP-sensitive potassium channel.

Formula: C₁₉H₂₂ClN₃O₅S₂

Color and Shape: Solid

Molecular weight: 471.98

Ref: TM-T71929