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CAS 158778-58-6

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DeMethyl Irbesartan

Description:
DeMethyl Irbesartan, identified by its CAS number 158778-58-6, is a chemical compound that serves as a derivative of Irbesartan, an angiotensin II receptor antagonist primarily used in the treatment of hypertension and heart failure. This compound is characterized by its structural modifications that involve the removal of a methyl group, which can influence its pharmacological properties. DeMethyl Irbesartan exhibits similar mechanisms of action to its parent compound, primarily by blocking the effects of angiotensin II, thereby promoting vasodilation and reducing blood pressure. The compound is typically administered in a pharmaceutical context, and its efficacy and safety profile are evaluated through clinical studies. In terms of physical properties, DeMethyl Irbesartan is expected to be a solid at room temperature, with solubility characteristics that may vary based on the solvent used. As with many pharmaceutical compounds, understanding its pharmacokinetics, metabolism, and potential side effects is crucial for its therapeutic application.
Formula:C24H26N6O
Synonyms:
  • Irbesartan impurity 2/Demethyl Irbesartan/Irbesartan Propyl Analog/2-Propyl-3-[[2-(2H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
  • Irbesartan Impurity (Demethyl Irbesartan)
  • DeMethyl Irbesartan
  • 3-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-2-Propyl-1,3-Diazaspiro[4.4]Non-1-En-4-One
  • Irbesartan Impurity 8 (Demethyl Irbesartan)
  • 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
  • 3-((2-(1H-Tetrazol-5-Yl)-[1,1-Biphenyl]-4-Yl)Methyl)-2-Propyl-1,3-Diazaspiro[4.4]Non-1-En-4-One(WXC02339)
  • Irbesartan Impurity-II
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