CAS 158792-24-6

COLLISMYCIN A

Description:

Collismycin A is a naturally occurring antibiotic that belongs to the class of compounds known as glycopeptides. It is produced by certain strains of the bacterium Amycolatopsis orientalis. This compound exhibits potent antibacterial activity, particularly against Gram-positive bacteria, including strains that are resistant to other antibiotics. Collismycin A functions by inhibiting cell wall synthesis, which is a critical process for bacterial growth and survival. Its structure features a complex arrangement of sugar moieties and aromatic rings, contributing to its biological activity. The compound has garnered interest in pharmaceutical research due to its potential therapeutic applications, especially in treating infections caused by multidrug-resistant organisms. Additionally, studies have indicated that Collismycin A may possess unique properties that differentiate it from other glycopeptide antibiotics, making it a subject of ongoing investigation in the field of medicinal chemistry. As with many antibiotics, the development of resistance is a concern, highlighting the importance of understanding its mechanism of action and optimizing its use in clinical settings.

Formula: C₁₃H₁₃N₃O₂S

InChI: InChI=1/C13H13N3O2S/c1-18-12-7-10(9-5-3-4-6-14-9)16-11(8-15-17)13(12)19-2/h3-8,16H,1-2H3/b11-8+

Synonyms:

• (2,2'-Bipyridine)-6-carboxaldehyde, 4-methoxy-5-(methylthio)-, oxime, (E)-
• (6E)-4-methoxy-5-(methylsulfanyl)-6-(nitrosomethylidene)-1,6-dihydro-2,2'-bipyridine
• Collismycin A

Collismycin-A (IB05208)

CAS: 158792-24-6

Formula: C₁₃H₁₃N₃O₂S

Purity: 93.6%

Color and Shape: White powder

Molecular weight: 275.0

Ref: 8R-JU0013

(E)-4-Methoxy-5-(methylthio)-[2,2'-bipyridine]-6-carbaldehyde oxime

CAS: 158792-24-6

Formula: C₁₃H₁₃N₃O₂S

Color and Shape: Solid

Molecular weight: 275.3262

Ref: IN-DA001QVH

Collismycin A

CAS: 158792-24-6

Collismycin A, from Streptomyces, has antibacterial, antiproliferative, and neuroprotective effects. It inhibits various cancer cells and is iron-complexing.

Formula: C₁₃H₁₃N₃O₂S

Color and Shape: Solid

Molecular weight: 275.33

Ref: TM-T35687

Collismycin A

CAS: 158792-24-6

Collismycin A is a biocompatible polymer with a strong antimicrobial activity. It has been shown to act as an inhibitor of the picolinic acid-dependent, nitrogen atom-containing enzyme, alpha-ketoglutarate aminotransferase. This inhibition leads to a decrease in the production of inflammatory mediators and autoantibodies. Collismycin A has also been shown to have immunomodulatory properties and may be useful for treating autoimmune diseases.

Formula: C₁₃H₁₃N₃O₂S

Purity: Min. 95%

Molecular weight: 275.33 g/mol

Ref: 3D-IGA79224