CAS 158836-71-6

nitroflurbiprofen

Description:

Nitroflurbiprofen is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic and anti-inflammatory properties. It is a derivative of flurbiprofen, which is known for its effectiveness in treating pain and inflammation. Nitroflurbiprofen features a nitro group, which enhances its pharmacological activity. The compound exhibits characteristics typical of NSAIDs, including the ability to inhibit cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins involved in inflammation and pain signaling. Nitroflurbiprofen is often studied for its potential applications in various inflammatory conditions and may also possess unique properties that differentiate it from other NSAIDs, such as improved gastrointestinal tolerability or enhanced efficacy. Its chemical structure includes a carboxylic acid functional group, contributing to its acidic nature, and it is generally administered in oral form. As with many NSAIDs, potential side effects may include gastrointestinal discomfort, cardiovascular risks, and renal effects, necessitating careful consideration in clinical use.

Formula: C₁₉H₂₀FNO₅

InChI: InChI=1/C19H20FNO5/c1-14(19(22)25-11-5-6-12-26-21(23)24)16-9-10-17(18(20)13-16)15-7-3-2-4-8-15/h2-4,7-10,13-14H,5-6,11-12H2,1H3

InChI key: InChIKey=DLWSRGHNJVLJAH-UHFFFAOYSA-N

SMILES: FC1=C(C=CC(C(C(OCCCCON(=O)=O)=O)C)=C1)C2=CC=CC=C2

Synonyms:

• (1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-, 4-(nitrooxy)butyl ester
• 4-(Nitrooxy)Butyl 2-(2-Fluorobiphenyl-4-Yl)Propanoate
• 4-(Nitrooxy)butyl 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetate
• Flurbinitroxy butyl ester
• Flurbinitroxybutylester
• Hct 1026
• Hct 1206
• NO-flurbiprofen
• Nitroxybutyl flurbiprofen
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, 4-(nitrooxy)butyl ester
• Nitroflurbiprofen

Nitroflurbiprofen

CAS: 158836-71-6

Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive

Formula: C₁₉H₂₀FNO₅

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 361.36

Ref: TM-T16329