CAS 158878-47-8

2H-Pyran-2-one,6-[(1E)-2-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-, (4R,6S)-

Description:

2H-Pyran-2-one, 6-[(1E)-2-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-, (4R,6S)-, with CAS number 158878-47-8, is a complex organic compound characterized by its pyranone structure, which features a six-membered ring containing both oxygen and carbon atoms. This compound exhibits a range of functional groups, including a hydroxyl group, which contributes to its potential reactivity and solubility in various solvents. The presence of a fluorophenyl group and a methoxymethyl substituent indicates that it may possess interesting electronic properties and biological activity. The stereochemistry denoted by (4R,6S) suggests specific spatial arrangements of atoms, which can influence the compound's interactions in biological systems. Overall, this substance may be of interest in medicinal chemistry and drug development due to its structural complexity and potential pharmacological properties. Further studies would be necessary to elucidate its specific applications and mechanisms of action.

Formula: C₂₆H₃₂FNO₄

2H-Pyran-2-one, 6-[(1E)-2-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-, (4R,6S)-

CAS: 158878-47-8

Formula: C₂₆H₃₂FNO₄

Color and Shape: Solid

Molecular weight: 441.535

Ref: IN-DA001QYT

Cerivastatin lactone

Controlled Product

CAS: 158878-47-8

Stability Hygroscopic
Applications Cerivastatin lactone is a metabolite of a competitive inhibitor of HMG-CoA reductase, Cerivastatin (C277000). Cerivastatin lactone shows inhibitory effects on CYP3A4/5 activity.
References Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996); Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996); Sakaeda, T., et. al.: Pharmaceut. Res., 23, 506 (2006)

Formula: C₂₆H₃₂FNO₄

Color and Shape: Neat

Molecular weight: 441.53

Ref: TR-C277005

Cerivastatin lactone

CAS: 158878-47-8

Cerivastatin lactone is a statin that inhibits the enzyme HMG-CoA reductase, which is involved in the synthesis of cholesterol. It also has anti-inflammatory properties. Cerivastatin lactone is used for the treatment of cardiovascular diseases and hypercholesterolemia. The drug can be administered orally and has been shown to have good bioavailability, with serum concentrations being detectable within 30 minutes after oral administration. Cerivastatin lactone has been shown to reduce serum concentration of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides, while increasing high-density lipoprotein cholesterol (HDL-C).

Formula: C₂₇H₃₄FNO₃

Purity: Min. 95%

Molecular weight: 439.6 g/mol

Ref: 3D-IGA87847

Cerivastatin lactone

CAS: 158878-47-8

Cerivastatin lactone, a metabolite of HMG-CoA reductase blocker Cerivastatin, inhibits CYP3A4/5.

Formula: C₂₆H₃₂FNO₄

Color and Shape: Solid

Molecular weight: 441.54

Ref: TM-T70419