CAS 158930-17-7: Frova
Description:Frova, with the CAS number 158930-17-7, is the brand name for the active pharmaceutical ingredient frovatriptan, which belongs to the triptan class of medications. It is primarily used for the acute treatment of migraine attacks. Frovatriptan functions as a selective agonist for serotonin receptors, specifically the 5-HT_1B and 5-HT_1D subtypes, which are involved in vasoconstriction and the modulation of neurotransmitter release. This mechanism helps alleviate migraine symptoms by reducing inflammation and constricting dilated blood vessels in the brain. Frovatriptan is characterized by its relatively long half-life compared to other triptans, allowing for prolonged efficacy in migraine relief. It is typically administered orally and is well-tolerated, with common side effects including dizziness, fatigue, and nausea. As with other triptans, it is contraindicated in patients with certain cardiovascular conditions due to the potential for vasoconstriction. Overall, frovatriptan is an effective option for managing acute migraine episodes.
Formula:C18H25N3O6
InChI:InChI=1/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2
- Synonyms:
- (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate
- Frovatriptan Succinate Monohydrate
- Frovelan
- Migard
- (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide
