CAS 158966-44-0
:3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE
Description:
3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine is a modified nucleoside that exhibits unique structural and chemical characteristics. This compound features a uridine backbone, which is a nucleoside composed of a ribose sugar and a uracil base, with specific modifications that enhance its stability and bioactivity. The presence of two benzoyl groups at the 3' and 5' positions contributes to its lipophilicity, potentially improving membrane permeability and cellular uptake. The 5-fluoro substitution on the uracil base can influence its interaction with nucleic acid targets and may enhance its antiviral or anticancer properties. Additionally, the 2'-O-methyl modification is known to confer resistance to enzymatic degradation, making this compound of interest in therapeutic applications. Overall, 3',5'-di-O-benzoyl-5-fluoro-2'-O-methyluridine is a chemically stable and biologically relevant molecule, often studied for its potential in drug development and molecular biology research.
Formula:C24H21FN2O8
Synonyms:- 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyl-D-uridine
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Found 3 products.
3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine
CAS:<p>3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine is a nucleoside that acts as an activator and phosphoramidite. The di-O-benzoyl group is used to protect the 2'-hydroxyl group during the synthesis of oligonucleotides. 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine has been shown to have anticancer activity against human breast cancer cells. It also inhibits the replication of DNA viruses, such as HIV, hepatitis B virus and herpes simplex virus type 1, and is active against influenza A virus. This compound has also been shown to inhibit the production of inflammatory cytokines in vitro.</p>Formula:C24H21FN2O8Purity:Min. 95%Molecular weight:484.44 g/mol
