The chemical substance with the name "(1R,3S,5Z)-3-Hydroxy-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexyl 2-bromoacetate" and CAS number "158983-23-4" is a complex organic compound characterized by its intricate stereochemistry and multiple functional groups. It features a hydroxy group, a methylene bridge, and a bromoacetate moiety, indicating potential reactivity and biological activity. The presence of multiple chiral centers suggests that it may exhibit stereospecific properties, which can influence its interactions in biological systems. The compound's structure includes a cyclohexyl ring and an indene derivative, contributing to its overall hydrophobic character. Such compounds are often studied for their potential applications in pharmaceuticals, agrochemicals, or as intermediates in organic synthesis. The specific arrangement of substituents and the stereochemistry can significantly affect the compound's physical properties, such as solubility, melting point, and reactivity, making it a subject of interest in medicinal chemistry and drug development.

(1R,3S,5Z)-3-Hydroxy-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexyl 2-bromoacetate

158983-23-4: The chemical substance with the name "(1R,3S,5Z)-3-Hydroxy-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexyl 2-bromoacetate" and CAS number "158983-23-4" is a complex organic compound characterized by its intricate stereochemistry and multiple functional groups. It features a hydroxy group, a methylene bridge, and a bromoacetate moiety, indicating potential reactivity and biological activity. The presence of multiple chiral centers suggests that it may exhibit stereospecific properties, which can influence its interactions in biological systems. The compound's structure includes a cyclohexyl ring and an indene derivative, contributing to its overall hydrophobic character. Such compounds are often studied for their potential applications in pharmaceuticals, agrochemicals, or as intermediates in organic synthesis. The specific arrangement of substituents and the stereochemistry can significantly affect the compound's physical properties, such as solubility, melting point, and reactivity, making it a subject of interest in medicinal chemistry and drug development.

<p>VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].</p>

CAS 158983-23-4

(1R,3S,5Z)-3-Hydroxy-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]cyclohexyl 2-bromoacetate

VDX-111

Ref: TM-T87611