Aristolochic acid IV is a naturally occurring compound primarily found in plants of the Aristolochia genus. It is classified as a phenanthrene derivative and is known for its potent biological activity. The compound has a molecular formula that reflects its complex structure, which includes multiple aromatic rings and functional groups. Aristolochic acid IV is recognized for its nephrotoxic and carcinogenic properties, raising significant health concerns, particularly in relation to its use in traditional medicine. Its mechanism of action involves the formation of DNA adducts, leading to mutagenic effects. The substance is also associated with aristolochic acid nephropathy, a condition characterized by kidney damage. Due to these adverse effects, many countries have restricted or banned the use of Aristolochia species in herbal remedies. In terms of physical properties, Aristolochic acid IV is typically a solid at room temperature and exhibits low solubility in water, but it is soluble in organic solvents. Its study is important for understanding both its pharmacological potential and its risks to human health.

Aristolochic acid IV

15918-62-4: Aristolochic acid IV is a naturally occurring compound primarily found in plants of the Aristolochia genus. It is classified as a phenanthrene derivative and is known for its potent biological activity. The compound has a molecular formula that reflects its complex structure, which includes multiple aromatic rings and functional groups. Aristolochic acid IV is recognized for its nephrotoxic and carcinogenic properties, raising significant health concerns, particularly in relation to its use in traditional medicine. Its mechanism of action involves the formation of DNA adducts, leading to mutagenic effects. The substance is also associated with aristolochic acid nephropathy, a condition characterized by kidney damage. Due to these adverse effects, many countries have restricted or banned the use of Aristolochia species in herbal remedies. In terms of physical properties, Aristolochic acid IV is typically a solid at room temperature and exhibits low solubility in water, but it is soluble in organic solvents. Its study is important for understanding both its pharmacological potential and its risks to human health.

CAS 15918-62-4

Aristolochic acid IV

Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8,10-dimethoxy-6-nitro-

Ref: IN-DA001QJF

Aristolochic acid D

Ref: 7W-GP1884