
CAS 1593842-75-1
:Nα-Fmoc-Nε-tetr-butyl-L-lysine
Description:
Nα-Fmoc-Nε-t-butyl-L-lysine is a protected amino acid commonly used in peptide synthesis. It features a phenylmethoxycarbonyl (Fmoc) group at the Nα position, which serves as a protective group that can be easily removed under basic conditions, allowing for selective deprotection during peptide assembly. The Nε position is modified with a t-butyl group, which provides steric hindrance and enhances the solubility of the amino acid in organic solvents, making it advantageous for solid-phase peptide synthesis. This compound retains the essential characteristics of lysine, including its basic nature due to the amino group on the side chain, which can participate in various chemical reactions. Its structure contributes to the overall stability and reactivity of peptides, influencing their folding and biological activity. Nα-Fmoc-Nε-t-butyl-L-lysine is typically utilized in the synthesis of peptides that require specific functionalization or modifications, making it a valuable tool in the field of medicinal chemistry and biochemistry.
Formula:C25H32N2O4
Synonyms:- L-Lysine, N6-(1,1-dimethylethyl)-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- Nα-Fmoc-Nε-tetr-butyl-L-lysine
- Fmoc-L-Lys(tBu)-OH
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