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CAS 159414-98-9

:

2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE

Description:
2'-Fluoro-5'-O-dimethoxytrityl-N4-acetyl-D-cytidine is a modified nucleoside that features a fluorine atom at the 2' position of the ribose sugar, which can enhance its stability and binding affinity in various biochemical applications. The dimethoxytrityl (DMT) group at the 5' position serves as a protective group, commonly used in the synthesis of oligonucleotides, allowing for selective reactions at other functional sites. The N4-acetyl modification on the cytosine base contributes to the compound's solubility and stability, making it suitable for use in nucleic acid research and therapeutic applications. This compound is characterized by its ability to participate in hydrogen bonding due to the presence of the cytosine base, while the modifications provide unique properties that can influence its reactivity and interaction with other biomolecules. Overall, 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE is an important tool in molecular biology, particularly in the synthesis of modified RNA and DNA strands.
Formula:C32H32FN3O7
InChI:InChI=1S/C32H32FN3O7/c1-20(37)34-27-17-18-36(31(39)35-27)30-28(33)29(38)26(43-30)19-42-32(21-7-5-4-6-8-21,22-9-13-24(40-2)14-10-22)23-11-15-25(41-3)16-12-23/h4-18,26,28-30,38H,19H2,1-3H3,(H,34,35,37,39)/t26-,28-,29-,30-/m1/s1
InChI key:InChIKey=JIFNUYITABZZQS-PYYPWFDZSA-N
SMILES:C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N2C(=O)N=C(NC(C)=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Synonyms:
  • 2'-Fluoro-N4-Acetyl-5'-O-DMT-2'-deoxycytidine
  • Cytidine, N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-
  • N-Acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluorocytidine
  • N4-Acetyl-2'-Deoxy-2'-Fluoro-5'-O-Dmt-D-Cytidine
  • N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine
  • N4-Acetyl-5'-O-(4,4'-Dimethoxytrityl)-2'-Fluoro-D-Cytidine
  • DMT-2'-F-Ac-dC
  • N-(1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyriMidin-4-yl)acetaMide
  • N4-Ac-DMT-2'-F-dC
  • N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
  • See more synonyms
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