CAS 159414-99-0

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Description:

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a complex nucleoside phosphoramidite used primarily in the synthesis of oligonucleotides. This compound features a modified cytidine base, which includes a fluorine atom at the 2' position, enhancing its stability and resistance to enzymatic degradation. The presence of the 4,4-dimethoxytrityl group at the 5' position serves as a protective group, facilitating the selective coupling during oligonucleotide synthesis. The N-acetyl group contributes to the solubility and stability of the molecule. Additionally, the 2-cyanoethyl-N,N-diisopropyl moiety at the 3' position is crucial for the formation of phosphodiester bonds, making it an essential component in the synthesis of DNA and RNA analogs. This compound is typically utilized in research and therapeutic applications, particularly in the development of antisense oligonucleotides and other nucleic acid-based technologies. Its unique structural features allow for enhanced performance in various biochemical applications.

Formula: C₄₁H₄₉FN₅O₈P

Synonyms:

• 5'-O-DMT-2'-F-dC(N-Ac)-3'-CEDPA
• 2'-F-Ac-dC Phosphoramidite
• 2'-Fluoro-N4-Acetyl-5'-O-DMT-2'-deoxycytidine-3'-CE-Phosphoramidite
• DMT-2-F-dC(AC/bz)-CE Phosphoramidite

2'-F-Ac-dC Phosphoramidite

CAS: 159414-99-0

Formula: C₄₁H₄₉FN₅O₈P

Purity: 95%

Color and Shape: Solid

Molecular weight: 789.8286

Ref: IN-DA007WK9

Dmt-2'-f-dc(ac) amidite

CAS: 159414-99-0

Dmt-2'-f-dc(ac) amidite

Purity: 98%

Color and Shape: Solid

Molecular weight: 789.83g/mol

Ref: 54-PC906344

N4-Acetyl-2''-deoxy-5''-O-DMT-2''-fluorocytidine 3''-CE phosphoramidite

CAS: 159414-99-0

Ref: 7W-GN8849

Dmt-2'-f-dc(ac) amidite

CAS: 159414-99-0

Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite compound utilized in the synthesis of cyclic purine dinucleotides.'

Formula: C₄₁H₄₉FN₅O₈P

Color and Shape: Solid

Molecular weight: 789.83

Ref: TM-T39062

5'-DMT-2'F-dC(Ac) CEP

CAS: 159414-99-0

Formula: C₄₁H₄₉FN₅O₈P

Molecular weight: 789.84

Ref: 4Z-A-267095

N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite

CAS: 159414-99-0

N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite is a monophosphate nucleoside analog that is synthesized in an acetylated form. It is an activator of DNA synthesis, and as such, has anticancer activity. This compound also inhibits the replication of DNA viruses and has antiviral activity against influenza virus. N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite has been shown to be effective in the prevention of HIV infection in vitro.

Formula: C₄₁H₄₉FN₅O₈P

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 789.83 g/mol

Ref: 3D-PA09679

Dmt-2′-f-dc(ac) amidite

CAS: 159414-99-0

Purity: 95%

Molecular weight: 789.842

Ref: 10-F987455