CAS 15944-34-0

7-Chloro-1H-[1,8]naphthyridin-2-one

Description:

7-Chloro-1H-[1,8]naphthyridin-2-one, with the CAS number 15944-34-0, is a heterocyclic organic compound characterized by its fused naphthyridine structure, which includes a chlorine substituent at the 7-position and a carbonyl group at the 2-position. This compound typically exhibits a pale yellow to light brown appearance and is soluble in organic solvents, reflecting its aromatic nature. The presence of the chlorine atom contributes to its reactivity and potential biological activity, making it of interest in medicinal chemistry and drug development. Its structure allows for various interactions with biological targets, which may include enzyme inhibition or receptor binding. The compound's properties, such as melting point, boiling point, and spectral characteristics (like UV-Vis and NMR), can vary based on purity and environmental conditions. Overall, 7-Chloro-1H-[1,8]naphthyridin-2-one is a valuable compound in research, particularly in the fields of pharmacology and organic synthesis.

Formula: C₈H₅ClN₂O

InChI: InChI=1S/C8H5ClN2O/c9-6-3-1-5-2-4-7(12)11-8(5)10-6/h1-4H,(H,10,11,12)

InChI key: InChIKey=VOFMYNBQUTUEOS-UHFFFAOYSA-N

SMILES: ClC=1NC=2C(C=CC(=O)N2)=CC1

Synonyms:

• 7-Chloro-1H-[1,8]naphthyridin-2-one
• 1,8-Naphthyridin-2(1H)-one, 7-chloro-
• 1,8-Naphthyridin-2-ol, 7-chloro-
• 7-Chloro-1,8-naphthyridin-2(1H)-one
• 7-Chloro-1,2-dihydro-1,8-naphthyridin-2-one

1,8-Naphthyridin-2(1H)-one, 7-chloro-

CAS: 15944-34-0

Formula: C₈H₅ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 180.5911

Ref: IN-DA001QPT

7-Chloro-1H-1,8-naphthyridin-2-one

CAS: 15944-34-0

7-Chloro-1H-1,8-naphthyridin-2-one

Purity: 97%

Ref: 54-OR1041727

7-Chloro-1,8-naphthyridin-2-ol

CAS: 15944-34-0

Formula: C₈H₅ClN₂O

Purity: 97%

Molecular weight: 180.59

Ref: 10-F240539

7-Chloro-1,8-naphthyridin-2-ol

CAS: 15944-34-0

7-Chloro-1,8-naphthyridin-2-ol is a nucleic acid that stabilizes duplexes and triplexes. It has an affinity for adenine bases in DNA, RNA, or triplexes. 7-Chloro-1,8-naphthyridin-2-ol also binds to mismatched nucleobases in the sequence of nucleic acids. This compound is a potent inhibitor of HIV replication and has been shown to inhibit the growth of cancer cells by targeting the enzyme topoisomerase II alpha.

Formula: C₈H₅ClN₂O

Purity: Min. 95%

Molecular weight: 180.59 g/mol

Ref: 3D-QAA94434