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CAS 159453-08-4

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[pTyr5] EGFR (988-993)

Description:
The chemical substance known as [pTyr5] EGFR (988-993) is a synthetic peptide that corresponds to a specific sequence derived from the epidermal growth factor receptor (EGFR), particularly focusing on the phosphorylated tyrosine residue at position 5 of the peptide sequence. This modification is crucial for the receptor's activation and subsequent signaling pathways involved in cell proliferation and differentiation. The peptide is typically used in research to study EGFR signaling, interactions with other proteins, and the effects of phosphorylation on receptor function. Its CAS number, 159453-08-4, uniquely identifies this compound in chemical databases. Characteristically, this peptide is soluble in aqueous solutions and may exhibit specific binding affinities to other proteins or antibodies, making it valuable in biochemical assays and therapeutic research. The study of such peptides contributes to the understanding of cancer biology, as aberrations in EGFR signaling are often implicated in various malignancies.
Formula:C31H45N6O17P
Synonyms:
  • L-Leucine, L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-O-phosphono-L-tyrosyl-
  • [pTyr5] EGFR (988-993)
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