CAS 159471-46-2
:5-Hydroxy-PhIP
Description:
5-Hydroxy-PhIP, with the CAS number 159471-46-2, is a derivative of the heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), which is known for its formation during the cooking of meat at high temperatures. This compound is characterized by the presence of a hydroxyl (-OH) group at the 5-position of the imidazo ring, which influences its chemical reactivity and biological activity. 5-Hydroxy-PhIP is of interest in toxicology and cancer research due to its potential role as a genotoxic agent, as it can form DNA adducts that may lead to mutations. The compound is typically studied in the context of its metabolic pathways, stability, and interactions with cellular systems. Its solubility, stability under various conditions, and reactivity with biological macromolecules are key characteristics that determine its behavior in biological systems. Understanding these properties is crucial for assessing its potential health impacts and mechanisms of action in the context of dietary exposure.
Formula:C13H12N4O
Synonyms:- 5-Hydroxy-PhIP
- 5H-Imidazo[4,5-b]pyridin-5-one, 2-amino-1,4-dihydro-1-methyl-6-phenyl-
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5-OH-PhIP
CAS:<p>5-OH-PhIP is a PhIP metabolite.</p>Formula:C13H12N4OColor and Shape:SolidMolecular weight:240.26
