CAS 1596-67-4

L-thyronine

Description:

L-thyronine, also known as L-T4 or thyroxine, is a synthetic form of the thyroid hormone thyroxine, which plays a crucial role in regulating metabolism, growth, and development in the body. It is a white to off-white crystalline powder that is soluble in water and has a slightly bitter taste. The chemical formula of L-thyronine is C15H11I4NNaO4, and it contains iodine, which is essential for its biological activity. L-thyronine is primarily used in the treatment of hypothyroidism and certain types of goiter, as it helps to restore normal thyroid hormone levels. Its mechanism of action involves binding to thyroid hormone receptors, influencing gene expression and metabolic processes. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Side effects may include symptoms of hyperthyroidism if overdosed. Due to its importance in thyroid function, L-thyronine is a critical therapeutic agent in endocrinology.

Formula: C₁₅H₁₅NO₄

InChI: InChI=1/C15H15NO4/c16-14(15(18)19)9-10-1-5-12(6-2-10)20-13-7-3-11(17)4-8-13/h1-8,14,17H,9,16H2,(H,18,19)

InChI key: InChIKey=KKCIOUWDFWQUBT-AWEZNQCLSA-N

SMILES: O(C1=CC=C(C[C@@H](C(O)=O)N)C=C1)C2=CC=C(O)C=C2

Synonyms:

• <span class="text-smallcaps">L</span>-Thyronine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxyphenyl)-
• Desiodothyroxine
• O-(4-Hydroxyphenyl)-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-Hydroxyphenyl)-L-tyrosine
• O-(4-Hydroxyphenyl)tyrosine
• Thyronine
• Thyronine, <span class="text-smallcaps">L</span>-
• β-(p-Hydroxyphenoxy)phenylalanine
• L-Thyronine
• L-Tyrosine, O-(4-hydroxyphenyl)-
• Thyronine, L-
• 3-[P-(P-HYDROXYPHENOXY)PHENYL]-L-ALANINE
• TYROSINE(4-HYDROXYPHENYL)-OH
• ALPHA-AMINO-BETA-(4-HYDROXYPHENOXYPHENYL) PROPIONIC ACID
• H-4-(4-HYDROXYPHENOXY)-PHE-OH
• H-TYR(4-HYDROXYPHENYL)-OH
• H-BETA-[4-(4-HYDROXYPHENOXY)-PHENYL]-ALA-OH
• S-THYRONINE
• H-THY-OH
• H-4-(4-Htdroxyphenoxy)-Phe-OH
• A-AMINO-B-(4-HYDROXYPHENOXYPHENYL) PROPIONIC ACID

L-Tyrosine, O-(4-hydroxyphenyl)-

CAS: 1596-67-4

Formula: C₁₅H₁₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 273.2839

Ref: IN-DA001R86

L-Thyronine

CAS: 1596-67-4

Molecular weight: 273.3

Ref: 7W-GM7326

L-Thyronine

CAS: 1596-67-4

L-Thyronine

Purity: 98%

Molecular weight: 273.29g/mol

Ref: 54-OR1032009

L-Thyronine

CAS: 1596-67-4

L-Thyronine is a hormone that is synthesized in the thyroid gland and has a variety of biological functions. It is used to treat congestive heart failure, atherosclerosis, and other types of heart disease. L-Thyronine binds to receptors on cells and activates them, which stimulates production of energy for the cell. L-Thyronine also increases the number of mitochondria in cells and regulates the production of nitric oxide, which plays an important role in vascular relaxation. L-Thyronine can be administered orally or intravenously as a solution. The clinical response to treatment is evaluated by measurement of serum thyroxin levels before and after administration of L-Thyronine.

Formula: C₁₅H₁₅NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 273.28 g/mol

Ref: 3D-FT36781

L-Thyronine, 95%

CAS: 1596-67-4

Applications L-Thyronine is a type of thyroid hormone. Thyroid hormones are important regulators of growth and maturation before birth in mammals.
References Harris, Shelley E., et al.: J. Physiol., 595, 3331 (2017);

Formula: C₁₅H₁₅NO₄

Purity: 95%

Color and Shape: Neat

Molecular weight: 273.28

Ref: TR-T922700

L-Thyronin extrapure, 98%

CAS: 1596-67-4

Formula: C₁₅H₁₅NO₄

Purity: 98%

Molecular weight: 273.28

Ref: SR-12558

L-Thyronine

CAS: 1596-67-4

Formula: C₁₅H₁₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 273.288

Ref: 10-F493036

L-Thyronine-13C6

Controlled Product

CAS: 1596-67-4

Applications L-Thyronine-13C6 is a labeled version of L-Thyronine (T922700). L-Thyronine (T922700) can be used in biological study for hyperphosphatemia, phosphoprotein phosphatases, and microparticle release in vascular endothelial cells.
References Abbasian, N., et al.: J. Am. Soc. Nephrol., 26, 2152-2162 (2016);

Formula: C₆C₉H₁₅NO₄

Color and Shape: Neat

Molecular weight: 279.24

Ref: TR-T922702