CAS 159610-89-6

(2S)-N-Fmoc-6-Azido-Hexanoic Acid

Description:

(2S)-N-Fmoc-6-Azido-Hexanoic Acid is a chemical compound characterized by its azido functional group and Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is commonly used in peptide synthesis. This compound features a hexanoic acid backbone, indicating it has a six-carbon chain, with the azido group (-N3) positioned at the sixth carbon. The Fmoc group serves to protect the amine functionality during synthetic processes, allowing for selective reactions. The presence of the azido group makes this compound particularly useful in click chemistry, facilitating the introduction of various functional groups through azide-alkyne cycloaddition reactions. Additionally, the stereochemistry indicated by (2S) suggests that the compound has a specific spatial arrangement, which can influence its reactivity and interactions in biological systems. Overall, (2S)-N-Fmoc-6-Azido-Hexanoic Acid is a versatile intermediate in organic synthesis and bioconjugation applications, particularly in the development of peptide-based therapeutics and materials.

Formula: C₂₁H₂₂N₄O₄

Synonyms:

• Fmoc-Lys(N3)-OH
• L-Norleucine, 6-azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• -fluoren-9-ylmethoxy)carbonyl]-
• Nα-Fmoc-Nε-azide-L-Lysine≥ 99.9% (HPLC, Chiral purity)
• (2S)-6-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
• N
• 6-Azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-norleucine
• H
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-azidohexanoic acid
• N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-diazo-L-lysine
• (2S)-N-FMoc-6-azido--Hexanoic acid
• FMoc-e-azido-Nle-OH
• 6-Azido-
• -[(9
• 6-Azido-N-Fmoc-L-norleucine
• FMoc-L-azidolysine
• (2S)-N-FMoc-5-azido- hexanoic acid
• Nα-Fmoc-Nε-azide-L-Lysine
• L
• FMoc-Lys(N2)-OH
• Fmoc-ε-azido-Nle-OH
• -norleucine
• (9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(N3)-OH

6-Azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-norleucine

CAS: 159610-89-6

Formula: C₂₁H₂₂N₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 394.43

Ref: 3B-A3023

Fmoc-ε-azido-Nle-OH

CAS: 159610-89-6

Lysine-derived building block for “click chemistry” and other reactions involving azides. The azido moiety of Lys(N₃) may also be selectively converted into an amino group with triphenylphosphine in the presence of water.

Formula: C₂₁H₂₂N₄O₄

Purity: 99.5%

Color and Shape: White Powder

Molecular weight: 394.43

Ref: 01-4072394

L-Norleucine, 6-azido-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 159610-89-6

Formula: C₂₁H₂₂N₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 394.4238

Ref: IN-DA001R8M

Fmoc-Lys(N3)

CAS: 159610-89-6

Fmoc-Lys(N3)

Formula: C₂₁H₂₂N₄O₄

Purity: 98%

Color and Shape: white crystalline powder

Molecular weight: 394.42378g/mol

Ref: 54-BIBP1082

Fmoc-Azido-Lys-OH

CAS: 159610-89-6

Fmoc-Azido-Lys-OH is a Building Block that contains the amino acid lysine and a divalent metal ion, such as zinc. This Building Block can be used in solid phase synthesis of peptides and proteins. Fmoc-Azido-Lys-OH has been shown to have neuroprotective effects against neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, by inhibiting the aggregation of protein.

Formula: C₂₁H₂₂N₄O₄

Purity: Min. 98.0 Area-%

Molecular weight: 394.43 g/mol

Ref: 3D-FAK-1903-PI

Fmoc-Lys(N3)-OH

CAS: 159610-89-6

Formula: C₂₁H₂₂N₄O₄

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 394.431

Ref: 10-F494322

Fmoc-Lys(N3)-OH

CAS: 159610-89-6

Fmoc-Lys(N3)-OH is a glutamic acid molecule with a specific lysine and histidine residue. It has been shown to be cytotoxic in vitro, specifically targeting cancer cells. Fmoc-Lys(N3)-OH can be conjugated to vancomycin or other molecules that are not normally cell permeable for the treatment of neurodegenerative diseases. The divalent nature of this molecule allows it to cross the blood-brain barrier. Solid phase synthesis is used to produce this compound, which is then purified by chromatography and characterized by mass spectrometry.

Formula: C₂₁H₂₂N₄O₄

Purity: Min. 95%

Molecular weight: 394.42 g/mol

Ref: 3D-FF72479