CymitQuimica logo

CAS 159610-93-2

:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-serine

Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-serine, commonly referred to as Fmoc-Ser(OMe)-OH, is a derivative of the amino acid serine, modified for use in peptide synthesis. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The O-methyl group on the serine side chain enhances its solubility and can influence the reactivity of the hydroxyl group. The presence of the Fmoc group allows for selective protection of the amino group, facilitating the stepwise assembly of peptides. This compound is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its applications are primarily in the field of biochemistry and molecular biology, particularly in the synthesis of peptides for research and therapeutic purposes. Proper handling and storage conditions are essential to maintain its stability and reactivity.
Formula:C19H19NO5
InChI:InChI=1S/C19H19NO5/c1-24-11-17(18(21)22)20-19(23)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16-17H,10-11H2,1H3,(H,20,23)(H,21,22)/t17-/m0/s1
InChI key:InChIKey=YFWAFELGMGZCHL-KRWDZBQOSA-N
SMILES:C(OC(N[C@@H](COC)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-3-methoxypropanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxypropanoicacid
  • <span class="text-smallcaps">L</span>-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-
  • Fmoc-(S)-2-Amino-3-Methoxypropionic Acid
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-<span class="text-smallcaps">L</span>-serine
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyl-L-serine
  • L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.