CAS 159634-47-6: Ibutamoren

Description: Ibutamoren, also known as MK-677, is a non-peptide growth hormone secretagogue that mimics the action of ghrelin, a hormone that stimulates appetite and growth hormone release. It is characterized by its ability to increase the secretion of growth hormone and insulin-like growth factor 1 (IGF-1) without significantly affecting cortisol levels. Ibutamoren is often studied for its potential applications in muscle wasting, obesity, and age-related conditions due to its anabolic properties. The compound is typically administered orally and has a long half-life, allowing for once-daily dosing. Its pharmacological profile suggests that it may enhance lean body mass and improve bone density, making it of interest in both clinical and athletic contexts. However, while it shows promise, further research is needed to fully understand its long-term effects, safety profile, and potential side effects, which may include increased appetite and transient changes in glucose metabolism. As with any substance affecting hormonal pathways, caution is advised in its use.

Formula: C₂₇H₃₆N₄O₅S

InChI: InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1

InChI key: InChIKey=UMUPQWIGCOZEOY-JOCHJYFZSA-N

SMILES: O=C(NC(C(=O)N1CCC2(C=3C=CC=CC3N(C2)S(=O)(=O)C)CC1)COCC=4C=CC=CC4)C(N)(C)C

Synonyms:

• 1'-(2-methylalanyl-O-benzyl-D-seryl)-1-(methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine]
• 1N-[1-Benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxo-(1R)-ethyl]-2-amino-2-methylpropanamide
• 2-Amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
• 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide
• L 163191
• Propanamide, 2-amino-N-((1R)-2-(1,2-dihydro-1-(methylsulfonyl)spiro(3H-indole-3,4'-piperidin)-1'-yl)-2-oxo-1-((phenylmethoxy)methyl)ethyl)-2-methyl-
• Propanamide, 2-amino-N-(2-(1,2-dihydro-1-(methylsulfonyl)spiro(3H-indole-3,4'-piperidin)-1'-yl)-2-oxo-1-((phenylmethoxy)methyl)ethyl)-2-methyl-, (R)-
• Unii-Gj0Egn38Ul
• Ibutamoren

Ibutamoren

CAS: 159634-47-6

• Formula: C₂₇H₃₆N₄O₅S
• Molecular weight: 528.67

Ibutamoren

CAS: 159634-47-6

Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, …

• Formula: C₂₇H₃₆N₄O₅S
• Purity: 97.59%
• Color and Shape: Solid
• Molecular weight: 528.66

MK 677

CAS: 159634-47-6

Agonist of ghrelin receptor; growth hormone secretagog

• Formula: C₂₈H₄₀N₄O₈S₂
• Purity: Min. 95 Area-%
• Color and Shape: Powder
• Molecular weight: 624.77 g/mol