CAS 1597403-47-8: N,N′-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]

Description: N,N′-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] is a synthetic organic compound characterized by its unique structural features, which include a cyclohexane backbone and two 4-chlorophenoxyacetamide functional groups. This compound is typically classified as an amide due to the presence of the amide functional group (-C(=O)N-). The trans configuration of the cyclohexane moiety contributes to its stereochemical properties, influencing its biological activity and potential applications. The presence of the 4-chlorophenoxy groups suggests that it may exhibit specific interactions with biological targets, potentially making it relevant in pharmaceutical research. Its molecular structure may also impart certain solubility and stability characteristics, which are critical for its behavior in various chemical environments. As with many synthetic compounds, understanding its reactivity, stability, and potential toxicity is essential for safe handling and application in research or industrial contexts. Further studies would be necessary to elucidate its complete profile, including its physical properties, biological activity, and potential uses.

Formula: C₂₂H₂₄Cl₂N₂O₄

InChI: InChI=1/C22H24Cl2N2O4/c23-15-1-9-19(10-2-15)29-13-21(27)25-17-5-7-18(8-6-17)26-22(28)14-30-20-11-3-16(24)4-12-20/h1-4,9-12,17-18H,5-8,13-14H2,(H,25,27)(H,26,28)/t17-,18-

InChI key: InChIKey=HJGMCDHQPXTGAV-IYARVYRRNA-N

SMILES: O=C(NC1CCC(NC(=O)COC2=CC=C(Cl)C=C2)CC1)COC3=CC=C(Cl)C=C3

Synonyms:

• SMDC 750213
• N,N′-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
• Acetamide, N,N′-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-
• Trans-ISRIB
• ISRIB

Acetamide, N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-

CAS: 1597403-47-8

• Formula: C₂₂H₂₄Cl₂N₂O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 451.343

ISRIB (trans-isomer)

CAS: 1597403-47-8

• Purity: 98.8%
• Molecular weight: 451.34g/mol

ISRIB (trans-isomer)

CAS: 1597403-47-8

ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG …

• Formula: C₂₂H₂₄Cl₂N₂O₄
• Purity: 97.86% - 99.27%
• Color and Shape: Solid
• Molecular weight: 451.34

ISRIB

CAS: 1597403-47-8

Applications ISRIB is a potent and selective PERK inhibitor. References Sidrauski, C., et al.: eLife, …

• Formula: C₂₂H₂₄Cl₂N₂O₄
• Color and Shape: Neat
• Molecular weight: 451.34

Isrib

CAS: 1597403-47-8

Inhibitor of the Integrated Stress Response

• Formula: C₂₂H₂₄Cl₂N₂O₄
• Purity: Min. 95%
• Molecular weight: 451.35 g/mol