CAS 159752-10-0

MK 0677

Description:

MK 0677, also known as MK-0677 or ibutamoren, is a non-peptide growth hormone secretagogue that mimics the action of ghrelin, a hormone that stimulates appetite and growth hormone release. It is primarily known for its potential to increase growth hormone levels and enhance muscle mass and strength, making it of interest in both medical and athletic contexts. MK 0677 functions by binding to the growth hormone secretagogue receptor (GHS-R), leading to increased secretion of growth hormone from the pituitary gland. This compound is often studied for its potential therapeutic applications in conditions such as growth hormone deficiency, cachexia, and age-related muscle loss. Additionally, MK 0677 has been investigated for its effects on body composition, metabolism, and appetite regulation. However, its use in sports and bodybuilding raises ethical concerns and is prohibited by many sports organizations. As with any substance that affects hormonal pathways, careful consideration of its safety profile, potential side effects, and long-term impacts is essential.

Formula: C₂₇H₃₆N₄O₅S·CH₄O₃S

InChI: InChI=1S/C27H36N4O5S.CH4O3S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27;1-5(2,3)4/h4-12,22H,13-19,28H2,1-3H3,(H,29,33);1H3,(H,2,3,4)/t22-;/m1./s1

InChI key: InChIKey=DUGMCDWNXXFHDE-VZYDHVRKSA-N

SMILES: S(C)(=O)(=O)N1CC2(C=3C1=CC=CC3)CCN(C([C@@H](COCC4=CC=CC=C4)NC(C(C)(C)N)=O)=O)CC2.S(C)(=O)(=O)O

Synonyms:

• 1'-(2-methylalanyl-O-benzyl-D-seryl)-1-(methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine] methanesulfonate
• Crescendo
• Ibutamoren Mesilate
• Ibutamoren Mesylate
• L-163191
• Mk-0677
• Mk-677
• Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1)
• Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, monomethanesulfonate
• Propanamide, 2-amino-N-[2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, (R)-, monomethanesulfonate

Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, methanesulfonate (1:1)

CAS: 159752-10-0

Formula: C₂₈H₄₀N₄O₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 624.7692

Ref: IN-DA001RDO

Ibutamoren Mesylate

CAS: 159752-10-0

Ibutamoren Mesylate

Purity: 97%

Molecular weight: 624.77g/mol

Ref: 54-OR1024976

Ibutamoren Mesylate

CAS: 159752-10-0

Ibutamoren Mesylate

Purity: ≥95%

Molecular weight: 624.77g/mol

Ref: 54-BUP14488

Ibutamoren Mesylate

CAS: 159752-10-0

Formula: C₂₇H₃₆N₄O₅S·CH₃SO₃H

Molecular weight: 528.67 96.10

Ref: 4Z-I-138002

Ibutamoren Mesylate

CAS: 159752-10-0

Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.

Formula: C₂₈H₄₀N₄O₈S₂

Purity: 97.98% - ≥98%

Color and Shape: Solid

Molecular weight: 624.77

Ref: TM-T7112

MK 677

CAS: 159752-10-0

Applications MK-677 is a potent, non-peptide ghrelin receptor agonist.
References Kirstie, A., et al.: Mol. Pharmacol., 76, 802 (2009); Birgitte, H. et al.: Mol. Pharmacol., 75, 44 (2009)

Formula: C₂₇H₃₆N₄O₅S·CH₄SO₃

Color and Shape: Neat

Molecular weight: 624.80

Ref: TR-M424990

MK 677

CAS: 159752-10-0

Agonist of ghrelin receptor; growth hormone secretagog

Formula: C₂₈H₄₀N₄O₈S₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 624.77 g/mol

Ref: 3D-FA76733