CAS 159776-69-9
:Cemadotin
Description:
Cemadotin, with the CAS number 159776-69-9, is a synthetic compound that belongs to the class of small molecule inhibitors. It is primarily recognized for its role as an antitumor agent, specifically targeting cancer cells by interfering with their proliferation. The mechanism of action involves the inhibition of certain cellular pathways that are crucial for cancer cell survival and division. Cemadotin has been studied for its potential effectiveness against various types of tumors, particularly in preclinical and clinical settings. Its chemical structure features specific functional groups that contribute to its biological activity and solubility properties. As with many pharmacological agents, the safety profile, including potential side effects and interactions with other medications, is an important consideration in its therapeutic use. Ongoing research continues to explore its efficacy, optimal dosing regimens, and potential applications in combination therapies for enhanced anticancer effects.
Formula:C35H56N6O5
InChI:InChI=1/C35H56N6O5/c1-22(2)28(37-32(43)29(23(3)4)38(7)8)34(45)39(9)30(24(5)6)35(46)41-20-14-18-27(41)33(44)40-19-13-17-26(40)31(42)36-21-25-15-11-10-12-16-25/h10-12,15-16,22-24,26-30H,13-14,17-21H2,1-9H3,(H,36,42)(H,37,43)/t26-,27-,28-,29-,30-/m0/s1
SMILES:CC(C)[C@@H](C(=O)N(C)[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=NCc1ccccc1)O)N=C([C@H](C(C)C)N(C)C)O
Synonyms:- N,N-Dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-N-benzyl-L-prolinamide
- Nsc D-669356
- Unii-6Sq8M7Zsfv
- L-Prolinamide, N,N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-N-(phenylmethyl)-
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Found 5 products.
Cemadotin
CAS:<p>Cemadotin is a peptide that activates an ion channel. Cemadotin is a potent and selective inhibitor of the calcium channel, L-type, alpha 1D (P/Q-type) in human erythrocytes. It inhibits cell proliferation and induces apoptosis in some cancer cells by inhibiting protein interactions. This peptide has been shown to be a potent antagonist of the neuropeptide Y receptor (Y1) with high affinity for this receptor. Cemadotin also has been shown to inhibit the binding of ligands to their receptors in a variety of cell types, including rat cortical neurons and human platelets.</p>Formula:C35H56N6O5Purity:Min. 95%Molecular weight:640.90 g/molcemadotin free base
CAS:Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocksFormula:C35H56N6O5Purity:98.70% - 99.64%Color and Shape:SolidMolecular weight:640.86
