CAS 15985-39-4

L-Methionine-DL-sulfoximine

Description:

L-Methionine-DL-sulfoximine, with the CAS number 15985-39-4, is a sulfoximine derivative of the amino acid methionine. This compound is characterized by the presence of a sulfoximine functional group, which consists of a sulfur atom bonded to both an oxygen atom and a nitrogen atom. It is typically a white to off-white crystalline solid that is soluble in water and exhibits a slightly acidic to neutral pH. L-Methionine-DL-sulfoximine is known for its role as a biochemical inhibitor, particularly in the context of plant physiology, where it can affect the synthesis of certain amino acids and influence metabolic pathways. Additionally, it has been studied for its potential applications in agriculture as a herbicide and in various biochemical research settings. Its stability and reactivity can be influenced by environmental conditions, making it important to handle it with care in laboratory settings. Overall, L-Methionine-DL-sulfoximine is a compound of interest in both biochemical research and agricultural applications.

Formula: C₅H₁₂N₂O₃S

InChI: InChI=1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1

InChI key: InChIKey=SXTAYKAGBXMACB-DPVSGNNYSA-N

SMILES: C([C@@H](C(O)=O)N)CS(C)(=N)=O

Synonyms:

• (2S)-2-Amino-4-(S-methylsulfonimidosyl)butanoic acid
• (2S)-2-Amino-4-[imino(methyl)oxo-λ6-sulfanyl]butanoic acid
• (2S)-2-amino-4-(S-methylsulfonimidoyl)butanoic acid
• 2-Amino-4-(S-Methylsulfonimidosyl)Butanoic Acid
• <span class="text-smallcaps">L</smallcap>-Methionine-<smallcap>DL</span>-sulfoximine
• <span class="text-smallcaps">L</span>-Methionine (SR)-sulfoximine
• <span class="text-smallcaps">L</span>-Methionine dl-sulfoximine
• <span class="text-smallcaps">L</span>-Methionine sulfoximine
• Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)-, (2S)-
• Glabrin
• Glabrin (acyclic amino acid)
• L-Methionine [R,S]-Sulfoximine
• L-Methionine sulfoximine, 98+%
• L-Methionine-Dl-Sulfoximine
• L-S-[3-Amino-3-Carboxypropyl]-S-Methylsulfoximine
• L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine
• MSX (L-Methionine sulfoximine)
• Methionine-dl-sulfoximine
• Sulfoximine, S-(3-amino-3-carboxypropyl)-S-methyl-, <span class="text-smallcaps">L</span>-(±)-
• Sulfoximine, S-(3-amino-3-carboxypropyl)-S-methyl-, L-(±)-

Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)-, (2S)-

CAS: 15985-39-4

Formula: C₅H₁₂N₂O₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 180.2254

Ref: IN-DA001RGK

L-Methionine-DL-sulfoximine

CAS: 15985-39-4

L-Methionine-DL-sulfoximine

Purity: ≥98%

Molecular weight: 180.23g/mol

Ref: 54-BUP13863

L-Methionine sulfoximine

CAS: 15985-39-4

L-Methionine sulfoximine

Formula: C₅H₁₂N₂O₃S

Purity: 98%

Color and Shape: white solid

Molecular weight: 180.23g/mol

Ref: 54-OR480433

L-Methionine (R,S)-sulfoximine

CAS: 15985-39-4

Formula: CH₃S(O)NH)CH₂CH₂CH(NH₂)CO₂H

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 180.2

Ref: 7W-GM6925

L-Methionine-DL-sulfoximine

CAS: 15985-39-4

MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.

Formula: C₅H₁₂N₂O₃S

Purity: 99.56% - ≥98%

Color and Shape: White Crystalline Powder

Molecular weight: 180.23

Ref: TM-T41299

L-Methionine [R,S]-Sulfoximine-13C5

Controlled Product

CAS: 15985-39-4

Applications L-Methionine [R,S]-Sulfoximine-13C5,15N is the isotope labelled analog of L-Methionine [R,S]-Sulfoximine. Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.
References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)

Formula: C₅H₁₂N₂O₃S

Color and Shape: White Solid

Molecular weight: 185.19

Ref: TR-M260502

L-Methionine [R,S]-Sulfoximine

Controlled Product

CAS: 15985-39-4

Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.
References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)

Formula: C₅H₁₂N₂O₃S

Color and Shape: Neat

Molecular weight: 180.23

Ref: TR-M260500

L-Methionine [R,S]-sulfoximine

CAS: 15985-39-4

L-Methionine [R,S]-sulfoximine is a sulfoximide that inhibits the synthesis of methionine. Methionine is an essential amino acid that is converted to homocysteine and then to cysteine in the body. L-Methionine [R,S]-sulfoximine has been shown to inhibit the conversion of methionine to cysteine in vivo by acting as a competitive inhibitor of methioninase.

Formula: C₅H₁₂N₂O₃S

Purity: (Elemental Analysis) Min. 97%

Color and Shape: Powder

Molecular weight: 180.23 g/mol

Ref: 3D-FM25156

2-amino-4-(S-methylsulfonimidoyl)butanoic acid

CAS: 15985-39-4

Formula: C₅H₁₂N₂O₃S

Purity: 97%

Color and Shape: No data available.

Molecular weight: 180.22

Ref: 10-F367480

L-Methionine Sulfoximine (MSX) extrapure, 95%

CAS: 15985-39-4

Formula: C₅H₁₂N₂O₃S

Purity: min.95.0%

Color and Shape: White to pale yellow to pale beige to pale brown., Crystalline powder, Clear to very slightly hazy

Molecular weight: 180.23

Ref: SR-98183