CAS 159857-60-0

Fmoc-Lys(MMt)-OH

Description:

Fmoc-Lys(MMt)-OH, also known as Fmoc-Lysine with a 4-methyltrityl (MMt) protecting group, is a derivative of lysine commonly used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The MMt group protects the side chain amino group of lysine, preventing unwanted reactions while facilitating the synthesis of complex peptides. This compound is typically characterized by its stability under basic conditions, making it suitable for solid-phase peptide synthesis. It is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The presence of the Fmoc group allows for easy removal under mild basic conditions, enabling the subsequent coupling of amino acids. Overall, Fmoc-Lys(MMt)-OH is a valuable building block in the field of peptide chemistry, particularly in the synthesis of peptides with specific structural and functional properties.

Formula: C41H40N2O5

InChI: InChI=1S/C41H40N2O5/c1-47-32-25-23-31(24-26-32)41(29-14-4-2-5-15-29,30-16-6-3-7-17-30)42-27-13-12-22-38(39(44)45)43-40(46)48-28-37-35-20-10-8-18-33(35)34-19-9-11-21-36(34)37/h2-11,14-21,23-26,37-38,42H,12-13,22,27-28H2,1H3,(H,43,46)(H,44,45)/t38-/m0/s1

InChI key: CTYHQVFFQRDJSN-LHEWISCISA-N

SMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCCC[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

Synonyms:

• N6-[Diphenyl(4-methoxyphenyl)methyl]-N2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine, FMOC-L-LYS(MMT)-OH
• N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine
• N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexan
• (S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-6-((4-methoxyphenyl)diphenylmethylamino)hexanoic acid

Fmoc-Lys(Mmt)-OH

CAS: 159857-60-0

Purity: 95%

Color and Shape: Solid

Molecular weight: 640.294

Ref: 10-F605816

Fmoc-Lys(4-methoxytrityl)-OH

CAS: 159857-60-0

Fmoc-Lys(Mmt) is a versatile tool for the synthesis of sensitive drugs, due to the easy removal of the 4-methoxytrityl protecting group under mild conditions by reagents such as dichloroacetic acid or chloroacetic acid in CH₂Cl₂ / anisole.

Formula: C₄₁H₄₀N₂O₅

Purity: 98.7%

Color and Shape: Orange Powder

Molecular weight: 640.78

Ref: 01-4028286

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid

CAS: 159857-60-0

Formula: C₄₁H₄₀N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 640.7667

Ref: IN-DA001RG2

Fmoc-Lys(Mmt)-OH

CAS: 159857-60-0

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid

Formula: C₄₁H₄₀N₂O₅

Purity: 95%

Molecular weight: 640.77

Ref: IN-DG233899

N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected

CAS: 159857-60-0

N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected

Formula: C₄₁H₄₀N₂O₅

Purity: >98%

Color and Shape: Solid

Molecular weight: 640.7667

Ref: 54-OR17117

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine

CAS: 159857-60-0

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine is a cyclic peptide that is synthesized using a liquid chromatograph. The synthesis of this compound requires a cyclic peptide, which is synthesized by solid phase methods. N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine has been found to be efficient in the industrial production of peptides with an amino acid sequence. This compound also has functional groups such as hydrophilic and labile, which are readily removed by trifluoroacetic acid.

Formula: C₄₁H₄₀N₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 640.77 g/mol

Ref: 3D-FF49453