CAS 159857-79-1

Val-cit-PAB-OH

Description:

Val-cit-PAB-OH, also known by its CAS number 159857-79-1, is a chemical compound that belongs to the class of peptide-based drug delivery systems. It is characterized by the presence of a valine-citrulline dipeptide linked to a p-aminobenzyl alcohol (PAB-OH) moiety. This structure is designed to enhance the solubility and stability of the compound, making it suitable for various pharmaceutical applications, particularly in targeted drug delivery and prodrug formulations. The valine and citrulline components contribute to its bioactivity, while the PAB-OH segment can facilitate the release of active pharmaceutical ingredients in a controlled manner. The compound's properties, such as solubility, stability, and bioavailability, are influenced by its molecular structure, making it a subject of interest in medicinal chemistry and drug development. Additionally, its potential applications may extend to cancer therapy and other therapeutic areas where targeted delivery is crucial.

Formula: C₁₈H₂₉N₅O₄

Synonyms:

• L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
• al-Cit-PAB-OH
• (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide
• Val-cit-PAB-OH
• (D)-VAL-CIT-PAB
• EOS-61316
• NH2-Val-Cit-PAB
• L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
• (S)-2-((R)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide

L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

CAS: 159857-79-1

Formula: C₁₈H₂₉N₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 379.4540

Ref: IN-DA001RG1

Val-cit-PAB-OH

CAS: 159857-79-1

Val-cit-PAB-OH

Purity: ≥98%

Molecular weight: 379.45g/mol

Ref: 54-BUP17544

Val-Cit-PAB

CAS: 159857-79-1

Val-Cit-PAB

Purity: 98%

Molecular weight: 379.45g/mol

Ref: 54-OR471212

Val-Cit-PAB-OH

CAS: 159857-79-1

Formula: C₁₈H₂₉N₅O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 379.46

Ref: 3B-V0155

Val-cit-PAB-OH

CAS: 159857-79-1

Val-cit-PAB-OH is an ADC linker that is cleavable.

Formula: C₁₈H₂₉N₅O₄

Purity: 99.11%

Color and Shape: Solid

Molecular weight: 379.45

Ref: TM-T17213

Val-Cit-PAB-OH

CAS: 159857-79-1

The Val-Cit-PAB linker is an activated peptide linker that is cleaved by cathepsin B. It enables the selective intracellular release of attached drugs in ADC applications.

Formula: C₁₈H₂₉N₅O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 379.45 g/mol

Ref: 3D-FV145679

Val-Cit-PAB-OH

CAS: 159857-79-1

Formula: C₁₈H₂₉N₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 379.461

Ref: 10-F519696