CAS 159858-22-7

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide, with CAS number 159858-22-7, is a synthetic compound primarily used in the field of medicinal chemistry and peptide synthesis. This compound features a complex structure that includes a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is commonly employed in solid-phase peptide synthesis to protect amino groups during the assembly of peptides. The presence of L-valine and L-ornithine residues indicates its potential role in peptide-based therapeutics. Additionally, the incorporation of an aminocarbonyl group and a hydroxymethylphenyl moiety suggests that it may exhibit specific biological activities or interactions, possibly enhancing its solubility or binding properties. The compound's characteristics, including its molecular weight, solubility, and stability, would be influenced by its functional groups and overall structure, making it a subject of interest for further research in drug development and biochemistry.

Formula: C₃₃H₃₉N₅O₆

InChI: InChI=1S/C33H39N5O6/c1-20(2)29(38-33(43)44-19-27-25-10-5-3-8-23(25)24-9-4-6-11-26(24)27)31(41)37-28(12-7-17-35-32(34)42)30(40)36-22-15-13-21(18-39)14-16-22/h3-6,8-11,13-16,20,27-29,39H,7,12,17-19H2,1-2H3,(H,36,40)(H,37,41)(H,38,43)(H3,34,35,42)/t28-,29-/m0/s1

InChI key: InChIKey=DALMAZHDNFCDRP-VMPREFPWSA-N

SMILES: C(OC(N[C@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)[C@H](C)C)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
• L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-
• (9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
• (9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(hydroxymethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]carbamate
• (9H-fluoren-9-yl)methyl((S)-1-((())-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
• (9H-fluoren-9-yl)methyl ((2S)-1-((1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
• Fmoc-Val-Cit-PAB-OH
• FMoc-Val-Cit-PAB
• Fmoc-val-citrulline-para-aminobenzyl-OH

Fmoc-Val-Cit-PAB-OH

CAS: 159858-22-7

Formula: C₃₃H₃₉N₅O₆

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 601.70

Ref: 3B-F1223

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

CAS: 159858-22-7

Formula: C₃₃H₃₉N₅O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 601.6927

Ref: IN-DA001RFX

Fmoc-Val-Cit-PAB

CAS: 159858-22-7

Fmoc-Val-Cit-PAB

Purity: ≥95%

Molecular weight: 601.69g/mol

Ref: 54-BUP13941

Fmoc-Val-Cit-PAB

CAS: 159858-22-7

Fmoc-Val-Cit-PAB

Purity: 99%

Molecular weight: 601.69g/mol

Ref: 54-OR471213

Trastuzumab Impurity 2 (Fmoc-Val-Cit-PAB-OH)

CAS: 159858-22-7

Formula: C₃₃H₃₉N₅O₆

Molecular weight: 601.70

Ref: 4Z-T-400002

Fmoc-Val-Cit-PAB

CAS: 159858-22-7

Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).

Formula: C₃₃H₃₉N₅O₆

Purity: 97.18%

Color and Shape: Solid

Molecular weight: 601.69

Ref: TM-T4678

Fmoc-Val-Cit-PAB

CAS: 159858-22-7

Purity: 97%

Color and Shape: Solid

Molecular weight: 601.704

Ref: 10-F987723

Fmoc-val-cit-pab

CAS: 159858-22-7

Fmoc-Val-Cit-Pab is a modulator that targets the HER2 receptor. The antibody is designed to bind to a specific region of the HER2 receptor, which may be involved in initiating the cancerous process. This antibody has shown promising results in preclinical studies and clinical trials for breast cancer with HER2 overexpression. Fmoc-Val-Cit-Pab can be used as an immunotherapy for patients with metastatic her2-positive cancers. It also has regulatory properties and does not react with normal cells, making it safer than other monoclonal antibodies.

Formula: C₃₃H₃₉N₅O₆

Purity: Min. 95%

Molecular weight: 601.69 g/mol

Ref: 3D-FF176695