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CAS 1599486-33-5

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Mal-PEG6-PFP

Description:
Mal-PEG6-PFP, or Maleimide-Polyethylene Glycol (PEG) with a six-unit chain and a pentafluorophenyl (PFP) group, is a bifunctional chemical compound commonly used in bioconjugation and drug delivery applications. The maleimide group allows for selective conjugation to thiol-containing molecules, such as proteins or peptides, facilitating the formation of stable thioether bonds. The PEG segment enhances solubility and biocompatibility, reducing immunogenicity and improving pharmacokinetics. The pentafluorophenyl moiety serves as a reactive handle for further chemical modifications or conjugations, providing versatility in the design of complex biomolecules. This compound is typically characterized by its ability to form stable conjugates, its hydrophilic nature due to the PEG chain, and its reactivity stemming from the maleimide and PFP groups. Overall, Mal-PEG6-PFP is valuable in the fields of drug development, diagnostics, and targeted therapies, where precise control over molecular interactions is essential.
Formula:C25H30F5NO10
Synonyms:
  • Mal-PEG6-PFP ester
  • Mal-PEG6-PFP
  • 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester
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