CAS 159989-65-8: Nelfinavir mesylate

Description: Nelfinavir mesylate is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of protease inhibitors, which work by inhibiting the HIV protease enzyme, thereby preventing the virus from maturing and replicating. The substance is a white to off-white crystalline powder, which is soluble in organic solvents but has limited solubility in water. Nelfinavir mesylate is typically administered orally and is often used in combination with other antiretroviral agents to enhance therapeutic efficacy and reduce the risk of resistance. Its pharmacokinetic profile indicates that it has a relatively short half-life, necessitating multiple daily doses for effective viral suppression. Common side effects may include gastrointestinal disturbances, such as diarrhea and nausea, as well as potential metabolic effects. As with other antiretroviral therapies, monitoring for drug interactions and adherence to treatment regimens is crucial for optimal patient outcomes.

Formula: C₃₂H₄₅N₃O₄S·CH₄O₃S

InChI: InChI=1S/C32H45N3O4S.CH4O3S/c1-21-25(15-10-16-28(21)36)30(38)33-26(20-40-24-13-6-5-7-14-24)29(37)19-35-18-23-12-9-8-11-22(23)17-27(35)31(39)34-32(2,3)4;1-5(2,3)4/h5-7,10,13-16,22-23,26-27,29,36-37H,8-9,11-12,17-20H2,1-4H3,(H,33,38)(H,34,39);1H3,(H,2,3,4)/t22-,23+,26-,27-,29+;/m0./s1

InChI key: InChIKey=NQHXCOAXSHGTIA-SKXNDZRYSA-N

SMILES: O=C(NC(CSC=1C=CC=CC1)C(O)CN2CC3CCCCC3CC2C(=O)NC(C)(C)C)C=4C=CC=C(O)C4C.O=S(=O)(O)C

Synonyms:

• (3S,4As,8As)-N-(1,1-Dimethylethyl)Decahydro-2-[(2R,3R)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)Amino]-4-(Phenylthio)Butyl]-3-Isoquinolinecarboxamide Mesylate
• (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide
• 3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1)
• 3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, monomethanesulfonate (salt)
• 3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, [3S-[2(2S*,3S*),3α,4aβ,8aβ]]-, monomethanesulfonate (salt)
• 8A-Beta))-A-Betmonomethanesulfonate(Salt)
• Ag-1343
• Droxy-2-Methylbenzoyl)Amino)-4-(Phenylthio)Butyl)-,(3S-(2(2,S*,3S*),3-Alpha,4
• Nelfin
• Nelfinavir mesilate
• Nelfinavir1
• Nelfinivir
• Viracept
• Nelfinavir mesylate

Nelfinavir Mesylate

CAS: 159989-64-7 159989-65-8

• Formula: C₃₂H₄₅N₃O₄S·CH₄O₃S
• Purity: >97.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 663.89

3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1)

CAS: 159989-65-8

• Formula: C₃₃H₄₉N₃O₇S₂
• Purity: 96%
• Color and Shape: Solid
• Molecular weight: 663.8881

Nelfinavir mesylate

CAS: 159989-65-8

• Formula: C₃₂H₄₅N₃O₄S·CH₃SO₃H
• Purity: (HPLC) ≥ 97.0%
• Color and Shape: White to off-white crystalline powder or solid
• Molecular weight: 663.89

Nelfinavir Mesylate

CAS: 159989-65-8

Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).

• Formula: C₃₃H₄₉N₃O₇S₂
• Purity: 95.81% - 98.27%
• Color and Shape: A White Or Almost White Powder
• Molecular weight: 663.89

Nelfinavir-d9

CAS: 159989-65-8

• Formula: C₃₂H₃₆D₉N₃O₄S
• Molecular weight: 576.84

Nelfinavir Mesylate

CAS: 159989-65-8

Applications Nelfinavir Mesylate is an antiviral. HIV protease inhibitor. It is a COVID19-related research product. …

• Formula: C₃₂H₄₅N₃O₄S·CH₄O₃S
• Color and Shape: Neat
• Molecular weight: 663.89

Nelfinavir mesylate

CAS: 159989-65-8

Anti-viral; HIV protease inhibitor

• Formula: C₃₃H₄₉N₃O₇S₂
• Color and Shape: White Powder
• Molecular weight: 663.89 g/mol