CAS 160003-66-7: Iniparib

Description: Iniparib, with the CAS number 160003-66-7, is a small molecule that was initially developed as a potential chemotherapeutic agent, particularly for the treatment of cancer. It is classified as a PARP (poly(ADP-ribose) polymerase) inhibitor, which means it interferes with the DNA repair mechanisms in cancer cells, thereby enhancing the effectiveness of certain chemotherapy agents. Iniparib is notable for its ability to selectively target cancer cells with defective DNA repair pathways, making it a candidate for combination therapies, especially in tumors with BRCA mutations. The compound has been studied in various clinical trials, primarily for breast cancer and other solid tumors. Its mechanism of action involves the inhibition of PARP enzymes, leading to the accumulation of DNA damage and ultimately triggering apoptosis in cancer cells. However, the clinical efficacy and safety profile of Iniparib have been subjects of debate, and further research is necessary to fully understand its therapeutic potential and limitations.

Formula: C₇H₅IN₂O₃

InChI: InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11)

InChI key: InChIKey=MDOJTZQKHMAPBK-UHFFFAOYSA-N

SMILES: O=C(N)C1=CC=C(I)C(=C1)N(=O)=O

Synonyms:

• AntiPARP-2
• Benzamide, 4-iodo-3-nitro-
• Bsi 201
• Iniparib
• Ino2Ba
• Niba
• Sar240550
• Sml 0623
• 4-Iodo-3-nitrobenzamide

Benzamide, 4-iodo-3-nitro-

CAS: 160003-66-7

• Formula: C₇H₅IN₂O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 292.0307

Iniparib

CAS: 160003-66-7

• Color and Shape: Yellow Powder
• Molecular weight: 292.03g/mol

Iniparib

CAS: 160003-66-7

• Purity: ≥98%
• Molecular weight: 292.03g/mol

Iniparib

CAS: 160003-66-7

• Formula: C₇H₅IN₂O₃
• Purity: >98.0%(GC)
• Color and Shape: White to Yellow powder to crystal
• Molecular weight: 292.03

Iniparib

CAS: 160003-66-7

Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).

• Formula: C₇H₅IN₂O₃
• Purity: 98.93%
• Color and Shape: Solid
• Molecular weight: 292.03

4-Iodo-3-nitrobenzamide

CAS: 160003-66-7

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 292.0320129394531

4-Iodo-3-nitrobenzamide

CAS: 160003-66-7

Iniparib is a cancer drug that belongs to the class of platinum-based chemotherapy drugs. It …

• Formula: C₇H₅IN₂O₃
• Purity: Min. 95%
• Molecular weight: 292.03 g/mol