CAS 160003-66-7
:Iniparib
Description:
Iniparib, with the CAS number 160003-66-7, is a small molecule that was initially developed as a potential chemotherapeutic agent, particularly for the treatment of cancer. It is classified as a PARP (poly(ADP-ribose) polymerase) inhibitor, which means it interferes with the DNA repair mechanisms in cancer cells, thereby enhancing the effectiveness of certain chemotherapy agents. Iniparib is notable for its ability to selectively target cancer cells with defective DNA repair pathways, making it a candidate for combination therapies, especially in tumors with BRCA mutations. The compound has been studied in various clinical trials, primarily for breast cancer and other solid tumors. Its mechanism of action involves the inhibition of PARP enzymes, leading to the accumulation of DNA damage and ultimately triggering apoptosis in cancer cells. However, the clinical efficacy and safety profile of Iniparib have been subjects of debate, and further research is necessary to fully understand its therapeutic potential and limitations.
Formula:C7H5IN2O3
InChI:InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11)
InChI key:InChIKey=MDOJTZQKHMAPBK-UHFFFAOYSA-N
SMILES:N(=O)(=O)C1=CC(C(N)=O)=CC=C1I
Synonyms:- AntiPARP-2
- Benzamide, 4-iodo-3-nitro-
- Bsi 201
- Iniparib
- Ino2Ba
- Niba
- Sar240550
- Sml 0623
- 4-Iodo-3-nitrobenzamide
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.
Benzamide, 4-iodo-3-nitro-
CAS:Formula:C7H5IN2O3Purity:97%Color and Shape:SolidMolecular weight:292.0307Iniparib
CAS:Formula:C7H5IN2O3Purity:>98.0%(GC)Color and Shape:White to Yellow powder to crystalMolecular weight:292.03Iniparib
CAS:<p>Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).</p>Formula:C7H5IN2O3Purity:98.93%Color and Shape:SolidMolecular weight:292.03
