CAS 16006-64-7

6-methylpurine 2'-deoxyriboside

Description:

6-Methylpurine 2'-deoxyriboside is a nucleoside derivative characterized by the presence of a purine base, specifically 6-methylpurine, linked to a deoxyribose sugar. This compound is notable for its structural similarity to adenosine, with the methyl group at the 6-position of the purine ring influencing its biological activity and interactions. It is typically a white to off-white solid and is soluble in polar solvents such as water and methanol, which facilitates its use in biochemical applications. The compound is of interest in molecular biology and pharmacology, particularly in studies related to nucleic acid metabolism and potential therapeutic applications. Its CAS number, 16006-64-7, allows for precise identification in chemical databases. As a nucleoside analog, it may exhibit unique properties in terms of incorporation into nucleic acids and modulation of enzymatic activities, making it a valuable tool in research settings focused on DNA and RNA processes.

Formula: C₁₁H₁₄N₄O₃

InChI: InChI=1/C11H14N4O3/c1-6-10-11(13-4-12-6)15(5-14-10)9-2-7(17)8(3-16)18-9/h4-5,7-9,16-17H,2-3H2,1H3

SMILES: Cc1c2c(ncn1)n(cn2)C1CC(C(CO)O1)O

Synonyms:

• Nsc 103543
• 9H-Purine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-methyl-
• 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-methyl-9H-purine
• 9-(2-deoxypentofuranosyl)-6-methyl-9H-purine
• 6-Methylpurine 2'-deoxyriboside
• 9-(2-Deoxy-β-D-erythropento furanosyl)-6-methyl-9H-purine
• 6-Methyl purine-2’-deoxy-beta-D-riboside, MePdR
• 6-METHYLPURINE-2-DEOXY-BETA-D-RIBOSIDE
• 9-(2-Deoxy-beta-D-ribofuranosyl)-6-methylpurine
• 6-Methylpurine-2’-deoxy-β-D-riboside
• 9H-Purine, 9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methyl-
• (2R,3S,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3-ol
• 9-(2-Deoxy-β-D-erythropento furanosyl)-6-methyl-9H-purine,6-Methyl purine-2’-deoxy-beta-D-riboside, prodrug of anticancer agent 6-methylpurine GL100333 (suicide gene toxin), gene therapy
• 9-(2-Deoxy-β-D-ribofuranosyl)-6-methylpurine

9-(2-Deoxy-β-D-erythropentofuranosyl)-6-methyl-9H-purine

CAS: 16006-64-7

Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; Prodrug of anticancer agent 6-methylpurine; used for gene therapy

Formula: C₁₁H₁₄N₄O₃

Color and Shape: Solid

Molecular weight: 250.25

Ref: TM-TNU0182

6-METHYLPURINE-2'-DEOXY-β-D-RIBOSIDE

CAS: 16006-64-7

Purity: 95.0%

Molecular weight: 250.258

Ref: 10-F527490

6-Methylpurine-2'-deoxyriboside

CAS: 16006-64-7

6-Methylpurine-2'-deoxyriboside (6MPdR) is a nucleoside analog that inhibits viral polymerase activity. It is used in the treatment of bowel diseases, such as inflammatory bowel disease and hepatitis C. 6MPdR can be used to treat cancer by inhibiting cellular proliferation and inducing apoptosis. This drug has been shown to inhibit leishmania growth in cell culture. 6MPdR can be administered orally or intravenously, and is pegylated for greater stability in the blood stream.

Formula: C₁₁H₁₄N₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 250.25 g/mol

Ref: 3D-NM46495