CAS 160146-17-8

Finrozole

Description:

Finrozole, with the CAS number 160146-17-8, is a chemical compound that belongs to the class of non-steroidal antiandrogens. It is primarily recognized for its potential use in the treatment of conditions related to androgen excess, such as certain types of prostate cancer. Finrozole functions by inhibiting the action of androgens, which are male hormones that can promote the growth of hormone-sensitive tumors. The compound exhibits a specific mechanism of action that involves blocking androgen receptors, thereby reducing the biological effects of androgens in target tissues. In terms of its physical properties, Finrozole is typically characterized by its molecular structure, which includes various functional groups that contribute to its pharmacological activity. Safety and efficacy profiles are essential for any therapeutic agent, and ongoing research continues to evaluate its potential applications in clinical settings. As with any chemical substance, proper handling and adherence to safety guidelines are crucial when working with Finrozole in laboratory or medical environments.

Formula: C₁₈H₁₅FN₄O

InChI: InChI=1/C18H15FN4O/c19-16-7-3-13(4-8-16)9-17(24)18(23-12-21-11-22-23)15-5-1-14(10-20)2-6-15/h1-8,11-12,17-18,24H,9H2/t17-,18+/s2

InChI key: InChIKey=SLJZVZKQYSKYNV-ZVOYONDMNA-N

SMILES: [C@H]([C@H](CC1=CC=C(F)C=C1)O)(C2=CC=C(C#N)C=C2)N3C=NC=N3

Synonyms:

• Benzonitrile, 4-[(1R,2S)-3-(4-fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl]-, rel-
• Benzonitrile, 4-[3-(4-fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl]-, (R*,S*)-
• Finrozole
• MPV-2213ad
• rel-4-[(1R,2S)-3-(4-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl]benzonitrile

Finrozole

CAS: 160146-17-8

Finrozole

Purity: ≥98%

Molecular weight: 322.34g/mol

Ref: 54-BUP03435

Finrozole

CAS: 160146-17-8

Finrozole is a synthetic aromatase inhibitor that inhibits the conversion of androgens to estrogen. It has been shown to be effective in treating metastatic breast cancer, as well as inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. Finrozole may also be used for the treatment of Alzheimer's disease due to its ability to inhibit mitochondrial uncoupling, which prevents ATP production. This drug is a chiral compound with two enantiomers: R-finrozole and S-finrozole. The R-enantiomer is more potent than the S-enantiomer. The elimination phase of finrozole is much shorter than other drugs in this class, making it a desirable option for patients who are undergoing chemotherapy or radiation therapy.

Formula: C₁₈H₁₅FN₄O

Purity: Min. 95%

Molecular weight: 322.34 g/mol

Ref: 3D-FF102319

Finrozole

CAS: 160146-17-8

Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.

Formula: C₁₈H₁₅FN₄O

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 322.34

Ref: TM-T27320