CAS 1601496-05-2

3-(Benzo[d]thiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine

CAS: 1601496-05-2

3-(Benzo[d]thiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine

Purity: 99%

Molecular weight: 377.5g/mol

Ref: 54-OR1074840

GSK-843

CAS: 1601496-05-2

GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be used as an adjunctive treatment for inflammation.

Formula: C₁₉H₁₅N₅S₂

Purity: 99.18%

Color and Shape: Solid

Molecular weight: 377.49

Ref: TM-T11474

GSK-843

CAS: 1601496-05-2

GSK-843 is a drug that interacts with the kinase activity of the protein kinase A (PKA), which is an enzyme that phosphorylates proteins. GSK-843 also modulates the PKA and protein kinase C (PKC) activities, which are enzymes involved in cell signaling. Treatment with GSK-843 led to a significant reduction in cell viability and necrotic cell death, as well as reduced hepatic steatosis in animals. This drug has been shown to suppress TNF-α, an inflammatory cytokine, and fatty acid synthase, an enzyme involved in lipid metabolism, which may contribute to its anticancer activity.

Formula: C₁₉H₁₅N₅S₂

Purity: Min. 95%

Molecular weight: 377.49 g/mol

Ref: 3D-BPC49605