CAS 160203-74-7

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine

CAS: 160203-74-7

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine is a Nucleoside Derivative - Didehydro-nucleoside; Fluoro-modified nucleoside.

Formula: C₁₁H₁₁FN₂O₅

Color and Shape: Solid

Molecular weight: 270.21

Ref: TM-TNU0997

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine

CAS: 160203-74-7

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.

Formula: C₁₁H₁₁N₂O₅

Purity: Min. 95%

Molecular weight: 251.22 g/mol

Ref: 3D-NA144872

1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil

CAS: 160203-74-7

1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.

Formula: C₁₁H₁₁FN₂O₅

Purity: Min. 95%

Molecular weight: 270.21 g/mol

Ref: 3D-NA182971