CAS 160296-13-9

but-2-yn-1-yl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine-3-carboxylate

Description:

But-2-yn-1-yl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine-3-carboxylate, with CAS number 160296-13-9, is a complex organic compound characterized by its unique structural features, including a but-2-yn-1-yl substituent and a benzothieno-pyridine core. This compound exhibits a range of functional groups, including an amino group, a hydroxyl group, and a carboxylate moiety, which contribute to its potential biological activity and solubility properties. The presence of the tetrahydrobenzothieno structure suggests that it may possess interesting pharmacological properties, possibly acting as a ligand or modulator in biological systems. Its molecular structure indicates that it may participate in hydrogen bonding and other intermolecular interactions, influencing its reactivity and stability. Additionally, the compound's synthesis and characterization would typically involve techniques such as NMR spectroscopy, mass spectrometry, and chromatography to confirm its identity and purity. Overall, this compound represents a significant interest in medicinal chemistry and drug development due to its intricate structure and potential therapeutic applications.

Formula: C₁₇H₁₈N₂O₃S

InChI: InChI=1/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19)

InChI key: InChIKey=JDTZAGLGBRRCJT-UHFFFAOYSA-N

SMILES: NC1=C2C3=C(SC2=NC(C)=C1C(OCC#CC)=O)CC(O)CC3

Synonyms:

• 2-Butyn-1-yl 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl[1]benzothieno[2,3-b]pyridine-3-carboxylate
• Sb 205384
• [1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester
• [1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butynyl ester
• But-2-yn-1-yl 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine-3-carboxylate
• SB 205384 solid
• 4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER
• 4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester
• 4-AMINO-7-HYDROXY-2-METHYL-5,6,7,8-TETRAHYDROBENZO[B]THIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID BUT-2-YNYL ESTER
• 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester

SB 205384

CAS: 160296-13-9

SB 205384 is a drug that binds to the all-trans retinoic acid (ATRA) receptor, which is found in cerebellar granule cells. SB 205384 has been shown to have anxiolytic effects in vivo and in vitro, as demonstrated by its ability to inhibit the release of potassium ions from cerebellar granule cells. The binding site of SB 205384 has been mapped to the ATRA agonist binding site on the α1 subunit of the GABA A receptor complex. This drug also blocks chloride channels, which may be responsible for its anxiolytic activity.

Formula: C₁₇H₁₈N₂O₃S

Purity: Min. 95%

Molecular weight: 330.4 g/mol

Ref: 3D-KGA29613